Causal Effects of 1400 Blood Metabolites And Sleep Disorders: A Mendelian Randomization Study
zhen ma,
zhao min,
zhao huanghong
et al.
Abstract:Background: There is growing evidence that sleep disorders (SD) affect changes in the body's metabolic microbiota, such as serum levels of glucose, lipid metabolites, insulin, adrenaline, and cortisol, which are all modified by sleep. However, the causal relationship between these serum metabolites and SD remains undetermined.
Methods: A comprehensive two-sample Mendelian randomization (MR) study was performed to investigate the causal relationship between blood microbiota characteristics and SD. Additionally,… Show more
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