Caught on Colonoscopy: Schistosomiasis Manifesting as a Single Colonic Polyp

Seidelman, Jessica; Hendershot, Edward F.; Henshaw, Nancy G.; Rein, Matthew

doi:10.1016/j.amjmed.2018.06.034

Cited by 3 publications

(1 citation statement)

References 9 publications

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“…Concomitantly, the demographic of ENDS users has shifted towards teens and young adults 6 . There is a growing concern of nicotine addiction among youth and for the use of ENDS to serve as a potential gateway for other tobacco products such as cigarettes 7 . In addition, reports of potential toxicity associated with ENDS are emerging, suggesting that these products are not harmless 8 – 10 .…”

Section: Introductionmentioning

confidence: 99%

Cigalike electronic nicotine delivery systems e-liquids contain variable levels of metals

Neu

Lee

Brandis

et al. 2020

Sci Rep

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Electronic nicotine delivery systems (ENDS) are prefilled, battery-operated products intended to deliver nicotine to the user via an inhaled complex aerosol formed by heating a liquid composed of propylene glycol and glycerol, also referred to as vegetable glycerin and collectively called e-liquid, that contains nicotine and various flavor ingredients. Since their introduction in 2006, the number of ENDS on the market has increased exponentially. Despite their growing ubiquity, the possible health risks associated with ENDS use remain poorly understood. One potential concern is the presence of toxic metals in the e-liquid and aerosol. Herein, we report the evaluation of the metal content in the e-liquids from a series of commercially available cigalike ENDS brands (various flavors) determined using inductively coupled plasma mass spectrometry (ICP-MS) following e-liquid extraction. Each brand of cigalike ENDS was purchased at least three times at retail outlets in the Baltimore, Maryland metropolitan region over a period of six months (September 2017 to February 2018). This allowed for comparison of batch-to-batch variability. Several potentially toxic metals, including lead, chromium, copper, and nickel were detected in the e-liquids. In addition, high variability in metal concentrations within and between brands and flavors was observed . The internal assembled parts of each cartridge were analyzed by X-ray imaging, before dissembling so that the materials used to manufacture each cartridge could be evaluated to determine the metals they contained. Following washing to remove traces of e-liquid, lead, chromium, copper and nickel were all detected in the cigalike ENDS prefilled cartridges, suggesting one potential source for the metals found in the e-liquids. Collectively, these findings can inform further evaluation of product design and manufacturing processes, including quantification of metal concentrations in e-liquids over foreseeable storage times, safeguards against high concentrations of metals in the e-liquid before and after aerosolization (by contact with a metal heating coil), and control over batch-to-batch variability.

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Section: Introductionmentioning

confidence: 99%

Cigalike electronic nicotine delivery systems e-liquids contain variable levels of metals

Neu

Lee

Brandis

et al. 2020

Sci Rep

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Imported human Schistosoma japonicum: A report on two cases in Filipino migrants present in Italy and a systematic review of literature

Vellere

Mangano

Cagno

et al. 2020

Travel Medicine and Infectious Disease

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Unique Case of a Hamartomatous Duodenal Polyp Associated With Intestinal Schistosomiasis

Gonzalez

Gupta

Rodríguez³

et al. 2021

ACG Case Rep J

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Schistosomiasis is a trematode infection rarely diagnosed in the United States. Intestinal involvement is common with chronic infection and causes abdominal pain, changes in bowel habits, hematochezia, and polyp formation. Chronic, disseminated infection can affect the intestines causing the aforementioned symptoms, but reports of intestinal polyps are rare. Most cases are inflammatory fibrous polyps in the colon. There are very few cases reported in the literature of hamartomatous polyps arising in the small intestine. We present the rare case of a U.S.-born, 35-year-old woman diagnosed with a large duodenal hamartomatous polyp in the setting of intestinal schistosomiasis.

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Caught on Colonoscopy: Schistosomiasis Manifesting as a Single Colonic Polyp

Cited by 3 publications

References 9 publications

Cigalike electronic nicotine delivery systems e-liquids contain variable levels of metals

Cigalike electronic nicotine delivery systems e-liquids contain variable levels of metals

Imported human Schistosoma japonicum: A report on two cases in Filipino migrants present in Italy and a systematic review of literature

Unique Case of a Hamartomatous Duodenal Polyp Associated With Intestinal Schistosomiasis

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