“…In total, 3 studies were conducted in the united States [24] , [25] , [27] , 4 in Europe [23] , [26] , [29] , [30] , 3 in Asia [19] , [20] , [22] , 1 in South America [28] , and 1 in South Africa [21] . Nine studies were published in 2020 [19] , [21] , [22] , [23] , [24] , [25] , [28] , [29] , [30] . The total number of patients was 10 females [19] , [21] , [23] , [25] , [26] , [27] , [29] , [30] and 9 males [20] , [22] , [24] , [26] , [28] , [30] .…”