2022
DOI: 10.1161/atvbaha.121.317187
|View full text |Cite
|
Sign up to set email alerts
|

Caught at the Scene of the Crime: Platelets and Neutrophils Are Conspirators in Thrombosis

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
5
0

Year Published

2022
2022
2023
2023

Publication Types

Select...
3
1

Relationship

1
3

Authors

Journals

citations
Cited by 4 publications
(5 citation statements)
references
References 43 publications
0
5
0
Order By: Relevance
“…Neutrophils and platelets are two major cell types responsible for thrombosis formation 23,35-37 . Our statistical analysis did not reveal any significant differences between the two groups, neither in the overall cohort ( Suppl Fig.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Neutrophils and platelets are two major cell types responsible for thrombosis formation 23,35-37 . Our statistical analysis did not reveal any significant differences between the two groups, neither in the overall cohort ( Suppl Fig.…”
Section: Resultsmentioning
confidence: 99%
“…Neutrophils and platelets are two major cell types responsible for thrombosis formation 23,[35][36][37] .…”
Section: Neutrophil and Platelet Counts Were Comparable In Patients W...mentioning
confidence: 99%
“…EVs derived from neutrophils, monocytes, and macrophages are released upon stimulation by inflammatory and damage mediators and/or pathogen-associated molecular patterns [ 117 , 118 ]. It has been demonstrated that patients with inflammatory and infectious diseases have an increased number of circulating EVs derived from immune cells [ 119 , 120 ] that contribute to the restoration of homeostasis. In addition to antimicrobial effects of neutrophil-derived EVs [ 121 ], they enhance the immunological role of their parent cells by increasing the expression of IL-6 and ICAM-1 on endothelial cells [ 122 ], thereby facilitating their migration across the endothelial barrier.…”
Section: Biology Of Extracellular Vesiclesmentioning
confidence: 99%
“…The pooled values were as follows: sensitivity = 0.68 (95% CI 0.45-0.84), specificity = 0.73 (95% CI 0.6-0.83), positive likelihood ratio = 2.5 (95% CI 1.8-3.4), negative likelihood ratio = 0.44 (95% CI 0.26-0.75), diagnostic odds ratio = 6 (95% CI [3][4][5][6][7][8][9][10][11], and SROC = 0.76 (95% CI: 0.73-0.8). These results indicated that NLR had moderate diagnostic accuracy for VTE.…”
Section: Diagnostic Value Of Nlr In Vtementioning
confidence: 99%
“…Neutrophils are thought to mediate the pathogenesis of VTE. 9 The initiation of thrombus formation involves an inflammatory process which induces activation of endothelial cells, platelets, and leukocytes. 10 Activated endothelial cells express P-selectin, an adhesion molecule that mediates the attachment of leukocytes and platelets.…”
Section: Introductionmentioning
confidence: 99%