“…In a formal framework it has allowed introducing in a many empirical chemical concepts like electronegativity [10], hardness [11], so-called reaction force [12], Fukui function [13], electrophilicity [14], electrofugality and nucleofugality [1,2,9,[15][16][17][18], nucleophilicity and solution phase ionization potentials, homofugality [19,20], nucleophilicity [21], among others. In particular, the introduction of concepts like electrophilicity and nucleophilicity to define electron deficient (electrophile) and electron rich (nucleophile) species has gained a continuous interest to construct empirical scales classifying atoms, molecules and charged species [22][23][24][25][26][27][28][29]. The availability of empirical scales of electrophilicity and nucleophilicity, usually based on kinetic parameters, has been very useful to rationalize the chemical reactivity, in terms of selectivity, reaction mechanisms, solvent, substituent effects, etc.…”