Catheter tip position as a risk factor for thrombosis associated with the use of subcutaneous infusion ports

Abstract

Compared to other reports, we noted a higher rate of thrombosis and port dysfunction. Since catheter tip position was a predisposing factor for developing a thrombosis, correct catheter position has to be ensured during placement. Prophylactic antithrombotic treatment might be beneficial in the event of failure to position the catheter correctly.

Factors on Patency Periods of Subcutaneous Central Venous Port: Long-Term Results of 1,408 Patients

“…Other complications are necrosis of the skin, malpositioning with nonfunction, displacement, and thrombosis, which are rare (2,(15)(16)(17). The catheter tip position is less subject to migration in the jugular venous entry (3).…”

“…The use of subcutaneous infusion ports has become the standard practice to obtain longterm venous access for administration of chemotherapy, antibiotics or parenteral nutrition (2). Subcutaneous venous chest ports were first surgically implanted by Niederhuber et al in 1982.…”

“…Studies have reported factors affecting the efficacy of subcutaneous venous chest port catheters placed into jugular or subclavian veins using a radiological technique (1)(2)(3)(4). There is still disagreement for this efficacy in these studies .…”

Epidemiology and prevention of catheter‐related thrombosis in patients with cancer

“…Furthermore, the use of prophylaxis is often unspecified and uncontrolled in these studies, leading to more uncertainty about the incidence of and risk factors for CRT. [58,59] Catheter tip position (proximal to SVC and RA junction) [16,[60][61][62][63][64] Number of lumens (triple > double > single) [13,64] Larger catheter caliber or diameter [65,66] Catheter occlusion [14] Insertion-related Vein entry (femoral > subclavian > jugular) [67,68] History of venous thromboembolism [13,16,72] Heritable thrombophilia [21][22][23] Infection [7,8,36] Tumour type and status [14,63] The largest study performed to date examined 17 baseline characteristics as potential risk factors for CRT [16]. In a patient data-level meta-analysis that included data from 5636 subjects with or without cancer who were enrolled in five randomized trials and seven prospective studies, in which 425 CRT events were observed, Saber et (Table 2).…”

Wszczepialne systemy dostępu naczyniowego u chorych na nowotwory

“…W innym badaniu retrospektywnym Caers i wsp. [14] wykazali ścisły związek między występowaniem zakrzepicy i dysfunkcji portów naczyniowych a położeniem końca cewnika powyżej jednej trzeciej dystalnej żyły głów-nej górnej. W badaniu tym zidentyfikowano również inne czynniki istotnie zwiększające ryzyko wystąpienia zakrzepicy.…”