Catheter sepsis due to coagulase-negative staphylococci in patients on total parenteral nutrition

Capell, Santiago; Liñares, Josefina; Sitges‐Serra, Antonio

doi:10.1007/bf02013459

Cited by 28 publications

(13 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Other potential sources of intraluminal contamination may be the hands of the medical or nurs ing staff manipulating the connections at hemodialysis, a leakage of contaminated hemodialysis fluid to the blood compartment, or blood or other contaminated solutions administered through the catheter during the dialysis session. Most authors, however, still accept the skin as the most important origin of catheter colonization [11,12,[20][21][22], Staphylococcus epidermidis is generally re garded as the most frequent colonizing microorganism [5,6,20,23] as was the cause in our study. However, only 3 of the 23 colonizing strains could be subsequently isolated in the blood.…”

Section: Discussionmentioning

confidence: 61%

Infection of Hemodialysis Catheters: Incidence and Mechanisms

et al. 1989

View full text Add to dashboard Cite

Fifty-three consecutive subclavian or jugular hemodialysis catheters inserted into 41 patients were prospectively studied over a period of 8 months in order to determine the incidence of infection and its mechanisms. The intravascular, intradermal and the Y catheter segments as well as both connections were cultured using a quantitative technique for the intraluminal surface. In addition, the intravascular and intradermal portions of the catheter were cultured using a semiquantitative technique for the external surface. Skin smears of the catheter entry site were also cultured, and blood cultures were similarly obtained if fewer developed. Twenty-nine of the 53 catheters (55%) were significantly colonized by one (19 cases) or more (10 cases) microorganisms. The source of the colonizing microorganisms was the skin in 17 cases (58 %), intraluminal in 5 (17 %), both routes in 5 (17 %) and others in 2 (6.8%). Staphylococcus epidermidis (22 cases) and Staphylococcus aureus (4 cases) were the bacteria most frequently isolated. Nine of the 53 catheterizations (17%) were complicated by catheter-related septicemia due to S. aureus in 4 cases, S. epidermidis in 3 cases, Streptococcus faecalis in 1 and Proteus vulgaris in 1. Catheter-related bacteremia contributed to a patient’s death in 1 case. Suppurative local infections of the catheter entry site developed in 3 cases, 2 of them with septicemia. We conclude that the rate of infection due to subclavian or jugular hemodialysis catheters is very high and that the skin is the most frequent origin of the microorganisms.

show abstract

Section: Discussionmentioning

confidence: 61%

Infection of Hemodialysis Catheters: Incidence and Mechanisms

et al. 1989

View full text Add to dashboard Cite

show abstract

“…The insertion point of the catheter is considered the main entry port for sepsis-causing microorganisms (5), which grow on the external part of the catheter, penetrating the blood stream through the intravascular portion (8,14). However, invasion from the catheter occurs less frequently through the use of contaminated intravenous fluids, from fungemia and from the central portion of the catheter (13).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Candida species in umbilical catheters implanted in newborns in Natal, Brazil

Fernandes¹,

Júnior²,

Oliveira³

et al. 2007

Braz. J. Microbiol.

View full text Add to dashboard Cite

All the newborns with umbilical venous catheters, hospitalized in the neonatal intensive care unit at Januário Cicco Maternity Hospital in Natal, Brazil, between January, 2003 and December, 2004 were studied. The prevalence of Candida species in the tips of intra-venous catheters was assessed, as well as the coexisting exposures that the patients were subjected to. Catheter tips were cultivated in blood agar and when yeast culture occurred, the colony was subcultivated for species identification through morphologic and biochemical assays. From a total of 240 catheters, 41 were positive for yeasts, and 34 were submitted to identification. The following agents were isolated: 13 C. albicans (38%), 10 Candida parapsilosis (29%), 8 C. tropicalis (20%), one C. guilliermondii (3%), one C. famata (3%) and one Trichosporon spp. (3%). Three patients among those with positive catheter tip fungal cultures were also hemoculture positive, with the same fungal species at both sites. Among the coexisting exposures, it should be pointed out that all the patients underwent broad spectrum antibiotic therapy, used a nasogastric probe, in addition to undergoing other invasive procedures such as mechanical ventilation and umbilical catheter implantation.

show abstract

“…Although much has been studied about the role of the catheter hub (1)(2)(3)(4) and exit site (5)(6)(7)(8) as a cause of catheter infection, bacteremia is increasingly recognized as a potential source. Previous work in our laboratory demonstrates that the fibrin sheath surrounding the catheter greatly enhances catheter colonization (CC) following bacteremia (9).…”

mentioning

confidence: 99%