Catheter-related infections in chronic hemodialysis: a clinical and economic perspective

Ștefan, Gabriel; Sica, Simona; Căpuşă, Cristina; Ailioaie, Oana Ramaiana; Mircescu, Gabriel

doi:10.1007/s11255-012-0244-7

Cited by 13 publications

(15 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This result is consistent with other reports showing end-stage renal failure is a risk factor of MRSA colonisation, infection and infection-related mortality. 25–30 Within the nested cohort of our patients who were either colonised or infected with MSSA/MRSA, the MRSA infection rate among those with end-stage renal failure was high (14/54; 26%) compared to those without end-stage renal failure (73/668; 12.3%). If our results are confirmed by other Australian ICUs, perhaps empirical vancomycin therapy should be considered in critically ill patients who have end-stage renal failure when serious systemic infection or bacteraemia is suspected, especially if they are known to be colonised with MRSA, or in centres where MRSA infection is endemic.…”

Section: Discussionmentioning

confidence: 92%

Positive nasal Staphylococcus aureus polymerase chain reaction assay is not sensitive in predicting concurrent or subsequent Staphylococcus aureus infection in critically ill patients

Kanagasingham

Robinson

2020

Anaesth Intensive Care

View full text Add to dashboard Cite

Staphylococcal infection is associated with significant morbidity and mortality in critically ill patients. Using data from 16,681 patients who had a nasal Staphylococcus aureus polymerase chain reaction (PCR) assay on admission to the intensive care unit (ICU) of Royal Perth Hospital between March 2006 and September 2016, this retrospective cohort study assessed whether nasal S. aureus colonisation on admission to an ICU was predictive of concurrent or subsequent S. aureus infections. Culture-proven S. aureus infections were identified using the hospital microbiology database. Of the 16,681 patients included, 565 (3.4%) had a positive methicillin-resistant S. aureus (MRSA) assay, 146 (0.9%) had a positive methicillin-sensitive S. aureus (MSSA) assay and eight (0.05%) had both positive MRSA and MSSA assays. Of those 565 patients with a positive MRSA PCR assay, 79 (13.8%) had concurrent or subsequent MRSA infections. Of those 146 patients with a positive MSSA PCR assay, only 5 (3.4%) had MSSA infection. The sensitivity and specificity for the MRSA PCR assay in predicting concurrent or subsequent MRSA infection were 72.7% (95% confidence intervals (CI) 63.4%–80.8%) and 97.0% (95% CI 96.8%–97.3%), respectively. The sensitivity and specificity for the MSSA PCR assay in predicting concurrent or subsequent MSSA infection were 3.3% (95% CI 1.1%–7.6%) and 99.1% (95% CI 98.9%–99.2%), respectively. Both nasal MRSA and MSSA PCR assays had a high specificity and negative predictive value in predicting MRSA and MSSA infections, respectively, suggesting that in centres without endemic S. aureus infections, a negative nasal MRSA or MSSA PCR assay may be useful to reduce unnecessary empirical antibiotic therapy against S. aureus.

show abstract

Section: Discussionmentioning

confidence: 92%

Positive nasal Staphylococcus aureus polymerase chain reaction assay is not sensitive in predicting concurrent or subsequent Staphylococcus aureus infection in critically ill patients

Kanagasingham

Robinson

2020

Anaesth Intensive Care

View full text Add to dashboard Cite

show abstract

“…It is well grounded in the literature that the catheter as access for HD, is associated with increased infections, and higher morbidity and mortality [18,19]. A study by Taylor, et al found that the relative risk of bacteremia in those using catheter for HD was estimated to be ten times greater than in patients with AVF.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the Impact of Nutritional Support on Quality of Life and Morbidity Indicators in Hemodialysis

Espirito¹,

Nestor²,

Rodrigues³

2018

J Nutri Med Diet Care

View full text Add to dashboard Cite

show abstract

“…In humans, CMV-specific CD4 + T cells represent 4% and 9.1% of total and memory T lymphocyte pools, respectively. 65 After a primary infection, CMV-specific CD4 + T cells can be detected from 7 to 10 days after the occurrence of viremia in SOTR, 66 and a delay in CD4 + T cell expansion is correlated with the severity of the disease.…”

Section: Cmv-specific Cd4 + T Cellsmentioning

confidence: 99%

Understanding human γδ T cell biology toward a better management of cytomegalovirus infection

Kaminski

Marsères

Cosentino

et al. 2020

Immunological Reviews

View full text Add to dashboard Cite

is a 200-to 300-nm virus, which belongs to the beta herpes virus family. CMV seroprevalence ranges from 40% in Canada to 90% in Brazil and China. 1 Whereas it is almost asymptomatic in immunocompetent individuals, it is responsible for significant morbidity and mortality in immunocompromised patients and pregnant women. In solid organ transplant recipients (SOTR), hematopoietic cell transplant recipients (HCTR), or human immunodeficiency virus (HIV) patients, CMV causes a multiorgan disease with a large clinical spectrum, which has been well defined recently in the CMV Drug Development Forum. 2 During pregnancy, CMV

show abstract

Catheter-related infections in chronic hemodialysis: a clinical and economic perspective

Cited by 13 publications

References 27 publications

Positive nasal Staphylococcus aureus polymerase chain reaction assay is not sensitive in predicting concurrent or subsequent Staphylococcus aureus infection in critically ill patients

Positive nasal Staphylococcus aureus polymerase chain reaction assay is not sensitive in predicting concurrent or subsequent Staphylococcus aureus infection in critically ill patients

Evaluation of the Impact of Nutritional Support on Quality of Life and Morbidity Indicators in Hemodialysis

Understanding human γδ T cell biology toward a better management of cytomegalovirus infection

Contact Info

Product

Resources

About