Catheter-directed Thrombolysis with the Endowave System in the Treatment of Acute Massive Pulmonary Embolism: A Retrospective Multicenter Case Series

Chamsuddin, Abbas; Nazzal, Lama; Kang, Brandon; Best, Irwin M.; Peters, Gail L.; Panah, S M Hosseini; Martin, Louis G.; Lewis, Curtis A.; Zeinati, Chadi; Ho, John W.; Venbrux, Anthony C.

doi:10.1016/j.jvir.2007.10.019

Cited by 76 publications

(46 citation statements)

References 29 publications

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“…[29][30][31] Chamsuddin, et al 29) concluded that USAT was an effective method for treating massive thrombolysis in their study of 10 acute massive PE patients. They emphasized the thrombolytic dose lowering effect of USAT.…”

Section: Discussionmentioning

confidence: 99%

Ultrasound Accelerated Thrombolysis May Be an Effective and Safe Treatment Modality for Intermediate Risk/Submassive Pulmonary Embolism

et al. 2016

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SummaryPulmonary embolism (PE) is a potentially life-threatening condition and the fact that 90% of PE originate from lower limb veins highlights the significance of early detection and treatment of deep vein thrombosis.1) Massive/high risk PE involving circulatory collapse or systemic arterial hypotension is associated with an early mortality rate of approximately 50%, in part from right ventricular (RV) failure.2) Intermediate risk/submassive PE, on the other hand, is defined as PE-related RV dysfunction, troponin and/or B-type natriuretic peptide elevation despite normal arterial pressure. 3)Without prompt treatment, patients with intermediate risk PE may progress to the massive category with a potentially fatal outcome. In patients with PE and right ventricular dysfunction (RVD), in hospital mortality ranges from 5% to 17%, significantly higher than in patients without RVD. 4,5) (Int Heart J 2016; 57: 91-95)

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Section: Discussionmentioning

confidence: 99%

Ultrasound Accelerated Thrombolysis May Be an Effective and Safe Treatment Modality for Intermediate Risk/Submassive Pulmonary Embolism

et al. 2016

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“…The bound DX-9065a is then protected from deactivation by anti-plasmin proteins. In patients with stroke [24], peripheral arterial occlusion [25], DVT [26] and PE [27,28] the EKOS system has been used. USAT treatment was used in 10 acute PE patients [27].…”

Section: Discussionmentioning

confidence: 99%

“…In patients with stroke [24], peripheral arterial occlusion [25], DVT [26] and PE [27,28] the EKOS system has been used. USAT treatment was used in 10 acute PE patients [27]. Our study was designed to investigate the contribution of DX-9065a, ultrasound and anticoagulation therapy on the recovery of right ventricular dilatation and clot burden.…”

Section: Discussionmentioning

confidence: 99%

Role of Catheter-Directed DX9065a Thrombolysis in the Treatment of Pulmonary Embolism

Xue¹

2015

Trop. J. Pharm Res

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“…Table 7 is a summary of the clinical trials and assessments of the efficacy of CDT with alteplase. 31,39,[41][42][43][44][45][46] Overall, CDT appears safe and effective. With CDT, medications can be delivered directly to the thrombus at a high concentration.…”

Section: Treatment Of Submassive Pulmonary Embolismmentioning

confidence: 91%

Alteplase Treatment of Acute Pulmonary Embolism in the Intensive Care Unit

Smithburger

Campbell

Kane‐Gill

2013

Critical Care Nurse

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Catheter-directed Thrombolysis with the Endowave System in the Treatment of Acute Massive Pulmonary Embolism: A Retrospective Multicenter Case Series

Cited by 76 publications

References 29 publications

Ultrasound Accelerated Thrombolysis May Be an Effective and Safe Treatment Modality for Intermediate Risk/Submassive Pulmonary Embolism

Ultrasound Accelerated Thrombolysis May Be an Effective and Safe Treatment Modality for Intermediate Risk/Submassive Pulmonary Embolism

Role of Catheter-Directed DX9065a Thrombolysis in the Treatment of Pulmonary Embolism

Alteplase Treatment of Acute Pulmonary Embolism in the Intensive Care Unit

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