Catheter-directed thrombolysis for acute limb ischaemia: An audit

Pascoe, Heather; Robertson, Donald

doi:10.4066/amj.2014.2065

Cited by 4 publications

(1 citation statement)

References 13 publications

(8 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…3,4,14,15 Exact status of the CDT procedure specifically for popliteal and infrapopliteal thromboocclusive lesions has not been documented. [16][17][18][19][20] Rheolytic thrombectomy (AngioJet) has been reported to be successful in approximately half of cases as a stand-alone technique. Moreover, it has been found to be only marginally effective in clearing more organized thrombus.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of intra-arterial catheter-directed thrombolysis for popliteal and infrapopliteal acute limb ischemia

Lian

Das

et al. 2020

Journal of Vascular Surgery

View full text Add to dashboard Cite

Objective: The purpose of this study was to examine the efficacy and safety of catheter-directed thrombolysis (CDT) for first-line treatment of popliteal and infrapopliteal acute limb ischemia. Methods: A total of 28 consecutive patients (30 limbs) who underwent CDT for treatment of popliteal and infrapopliteal acute limb ischemia of thromboembolic origin between March 2012 and December 2017 were enrolled in this study. Per the Society for Vascular Surgery, limbs were classified into three runoff score groups: <5, good; 5 to 10, compromised; and >10, poor. The primary end points were primary patency and limb salvage assessed by Kaplan-Meier survival analysis. Secondary end points were technical success and clinical success. The Society for Vascular Surgery-recommended scale for gauging changes in clinical status was used to assess clinical success. Safety of the procedure was evaluated on the basis of periprocedural complications according to the Society of Interventional Radiology classification system. Results: Technical success was achieved in 25 (83.33%) treated limbs. Improved clinical status (grade þ3/þ2) was achieved in 93.33% of limbs. Primary patency and limb salvage for the entire cohort were 76.67% and 90% at 6 months and 60.0% and 76.67% at 12 months, respectively. The patency rate at 6 months and 12 months was 91.67% and 83.33% for the good runoff group, 80% and 60% for the compromised runoff group, and 50% and 25% for the poor runoff group, respectively. The patency rate of the good runoff group was significantly higher compared with that of the poor runoff group (P ¼ .004). Major amputation rate and mortality rate were 16.67% and 7.14%, respectively, at 12 months. The reintervention rate was 3.57% at 6 months and 21.42% at 12 months. Conclusions: CDT is safe and effective for revascularization of smaller vessel acute arterial thromboembolism as a primary therapy. However, more studies with a larger sample are warranted.

show abstract

Section: Discussionmentioning

confidence: 99%

Efficacy of intra-arterial catheter-directed thrombolysis for popliteal and infrapopliteal acute limb ischemia

Lian

Das

et al. 2020

Journal of Vascular Surgery

View full text Add to dashboard Cite

show abstract

Thrombolysis in Acute Lower Limb Ischemia: Review of the Current Literature

Theodoridis

Davos

Dodos

et al. 2018

Annals of Vascular Surgery

View full text Add to dashboard Cite

Optimizing critical care of the trauma patient at the intermediate care unit: a cost-efficient approach

Plate

Peelen

Leenen

et al. 2018

Trauma Surg Acute Care Open

View full text Add to dashboard Cite

BackgroundThe aim of this study was to describe the case load, safety, and cost savings of critical care of the trauma patient provided at the surgical intermediate care unit (IMCU).MethodsThis cohort study included all trauma admissions between January 1, 2011 and January 7, 2015 at the general intensive care unit (ICU), stand-alone neuro(surgical) IMCU, and stand-alone (trauma) surgical IMCU. Trauma mechanism, Abbreviated Injury Scale score and Injury Severity Score (ISS), vital signs, laboratory parameters, admission duration, intubation duration, ICU transfer, and in-hospital mortality were prospectively collected. Hypothetical cost savings were calculated using the fixed cost price per IMCU (US$1500) and ICU (US$2500) admission day.ResultsA total of 1320 admissions were included, 675 (51.1%) at the IMCU and 645 (48.9%) at the ICU. Patients admitted at the IMCU had a median ISS of 17 (11, 22). Their median duration of admission was 32.8 hours (18.8, 62.5). At the IMCU, one patient died due to aneurogenic shock. A subsequent ICU transfer was required in 38 (5.6%) IMCU admissions. Of these transfers, four patients died due to neurological deterioration. At the ICU, the median ISS was 22 (14, 30). Nearly all (n=620, 96.3%) ICU trauma patients required mechanical ventilation. Expected total cost savings due to the presence of the IMCU were US$1 772 785.DiscussionA substantial amount of trauma patients in need of critical care can safely be admitted at the IMCU, without the need for further mechanical ventilation. Thereby, the IMCU could fulfill an essential cost-saving role in the management of severely injured trauma patients.Level of evidenceLevel IV.

show abstract

Catheter-directed thrombolysis for acute limb ischaemia: An audit

Cited by 4 publications

References 13 publications

Efficacy of intra-arterial catheter-directed thrombolysis for popliteal and infrapopliteal acute limb ischemia

Efficacy of intra-arterial catheter-directed thrombolysis for popliteal and infrapopliteal acute limb ischemia

Thrombolysis in Acute Lower Limb Ischemia: Review of the Current Literature

Optimizing critical care of the trauma patient at the intermediate care unit: a cost-efficient approach

Contact Info

Product

Resources

About