Catheter-directed thrombolysis and/or thrombectomy with selective endovascular stenting as alternatives to systemic anticoagulation for treatment of acute deep vein thrombosis

Endovascular treatment and long-term results of postpartum deep vein thrombosis in 18 patients

“…A similar favorable outlook has been presented in a report by Sillesen et al, (19) who noted that, after an average follow-up of 24 months, iliofemoral DVT patients treated by CDT had no recurrent thromboses. Catheterdirected endovascular treatment is more effective at improving patient symptoms and removing thrombi than anticoagulant therapy alone (3,20,21). Other endovascular methods include MAT, during which the thrombus is aspirated through large-bore (7 F to 9 F) guiding catheters, and percutaneous mechanical thrombectomy, during which a mechanical device causes microfragmentation of the thrombus followed by aspiration or lysis of the clot in the vessel.…”

Endovascular treatment of iliofemoral deep vein thrombosis in pregnancy using US-guided percutaneous aspiration thrombectomy

“…Demirturk et al (30) reported that endovascular treatment of postpartum iliofemoral DVT (within 42 days of childbirth) with PAT alone or combined with CDT was rapid, very safe and resulted in a very high rate of thrombus removal in 18 patients. In a previous study (14), a pregnant woman with DVT underwent percutaneous mechanical thrombectomy with the use of venograms because pregnancy was considered a contraindication to thrombolysis. Thrombus removal using PAT with or without fluoroscopy guidance has not been used to date in pregnant women with iliofemoral DVT.…”

“…Nonetheless, there are a few publications describing thrombolytic therapy of DVT with good success during pregnancy and peri-or postpartum period (10)(11)(12)(13). In a previous study (14), a pregnant woman with DVT was treated using percutaneous mechanical thrombectomy under venographic guidance with contrast agent. Percutaneous aspiration thrombectomy (PAT) with or without fluoroscopy guidance in preg- nant women with iliofemoral DVT has not been reported to date.…”

Diagnosis and Treatment of Lower Extremity Deep Vein Thrombosis: Korean Practice Guidelines

“…High success rates of clot lysis have been reported in studies assessing the effect of combining CDT with PMT, balloon maceration, or aspiration thrombectomy [161][162][163][164][165][166][167]. Although these methods are generally considered as safe treatments with lower dose and shorter treatment time, they have not been documented by large randomized controlled trials.…”