Catheter-Based Polarization Sensitive Optical Coherence Tomography Using Similar Mueller Matrix Method

Tao, Kuiyuan; Sun, Keliang; Ding, Zhenyang; Ma, Yan; Kuang, Hao; Zhao, Huishuo; Lai, Tianduo; Zhou, Yuqiu; Liu, Tiegen

doi:10.1109/tbme.2019.2908031

Cited by 9 publications

(8 citation statements)

References 30 publications

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“…We compare experimental results of depolarization samples, including microsphere suspensions and multiple biological tissues processed by the EMDI, DI, and DOPU using the catheter-based PS-OCT system. The experimental configuration of the catheter-based PS-OCT system has been previously described as depicted in Figure . Our experimental setup utilizes the depth multiplexing method based on a polarization-maintaining fiber (PMF).…”

Section: Methodsmentioning

confidence: 99%

“…25,34 We use SMM and MMA methods to demodulate the simulation data to obtain the spatial PS-OCT image. 25,28,34 ROR are selected as 2560 pixels on the top area, and reference points for SMM and MMA are selected as a horizontal 1-pixel-width line with 512 pixels on the simulating tissue surface. 25 We calculate EMDI, DI, and DOPU based on simulation images under different g and SNR values, and then these results contrast by setting true DI and DOPU shown in Figure 2(a) shows that DOPU, DI, and EMDI for a nondepolarized simulation material with g = 1 among additive noise from SNR = 0 to 15.…”

Section: Monte Carlo Simulationmentioning

confidence: 99%

“…For each simulation, two different SOPs of simulated lights are successively launched into the simulating tissue, and their output signals are collected by H and V channels, respectively. So the noises would appear not only on the intensity but also all 4 elements of Jones and 16 entries of Mueller matrices. , We use SMM and MMA methods to demodulate the simulation data to obtain the spatial PS-OCT image. ,, ROR are selected as 2560 pixels on the top area, and reference points for SMM and MMA are selected as a horizontal 1-pixel-width line with 512 pixels on the simulating tissue surface . We calculate EMDI, DI, and DOPU based on simulation images under different g and SNR values, and then these results contrast by setting true DI and DOPU shown in Figure .…”

Section: Monte Carlo Simulationmentioning

confidence: 99%

“…However, to achieve proper depolarization quantification by DI, a prerequisite is that the Mueller matrix should collect the depolarization effectively. In terms of recording depolarization by a Mueller matrix from PS-OCT, we previously proposed a similar Mueller matrix (SMM) for polarization determination and Mueller matrix incoherent averaging method (MMA) in the catheter-based PS-OCT. , In SMM, the DI can be calculated from a depolarization matrix, which is decoupled from birefringence and diattenuation matrices by Lu–Chipman decomposition. However, traditional DI cannot separate medium depolarization and noise-induced depolarization.…”

Section: Introductionmentioning

confidence: 99%

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Estimation of Medium Depolarization Index with Noise Immunity in Catheter-Based PS-OCT toward Vascular Plaques Detection

Li,

Ding,

et al. 2024

Chemical & Biomedical Imaging

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Medium depolarization imaging by catheter-based polarization-sensitive optical coherence tomography (PS-OCT) can provide valuable insight into significant features of lipid, macrophages, and cholesterol crystals in atherosclerotic vulnerable plaques. In this paper, we demonstrate a method to achieve an accurate estimation of the medium depolarization index (EMDI) with noise immunity in catheter-based PS-OCT. EMDI is calculated by an iterative approximation based on Lu−Chipman matrix decomposition and Frobenius norm judgment of incoherent averaging of Mueller matrices. Monte Carlo simulation results verify that the medium depolarization measurement by EMDI is 3.3 times more accurate compared with those of the depolarization index (DI) and degree of polarization uniformity (DOPU). In experiments, we design a microsphere suspension with various concentrations and measure EMDI under different additive noise. Consistently, the measurement accuracy by EMDI is increased 2.85 times compared to those by DI and DOPU. For vascular plaques detection, we use protein and cholesterol gel as plaque phantoms. Based on PS-OCT images of plaque phantom in vitro and in ex vivo porcine coronary artery, the recognition rate of plaque by EMDI is 2.99 to 4.65 times higher than those by DI and DOPU evaluated by spatial response of the Laplacian operator (SRLO).

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Section: Methodsmentioning

confidence: 99%

Section: Monte Carlo Simulationmentioning

confidence: 99%

Section: Monte Carlo Simulationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Estimation of Medium Depolarization Index with Noise Immunity in Catheter-Based PS-OCT toward Vascular Plaques Detection

Li,

Ding,

et al. 2024

Chemical & Biomedical Imaging

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“…Considering the literature, to our knowledge, there is a gap in the studies regarding the LED NIR light beam patterns within the soft tissue. A number of the reported studies in this subject have focused on the beam patterns of the light in the fluorescence wavelengths region and in other areas of applications including the treatment of skin and mucosal diseases and Optical Coherent Tomography [25,[43][44][45][46][47][48][49][50][51][52].…”

Section: Introductionmentioning

confidence: 99%

Enhancement of optical penetration depth of LED-based NIRS systems by comparing different beam profiles

Mirbagheri¹,

Hakimi²,

Ebrahimzadeh³

et al. 2019

Biomed. Phys. Eng. Express

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Near-Infrared Spectroscopy (NIRS) is a non-invasive brain imaging technique involving the quantification of oxy and deoxy-hemoglobin concentrations resolved from the measurement of Near-Infrared (NIR) light attenuation within the tissue. Previous studies have shown that NIR light is more influenced by the optical properties of the superficial layers than those of the deeper target layers such as cortex. NIR light produced by the Laser source penetrates deeper regions of the tissue rather than the LED source although Laser needs more expensive instrumentation. In this study, we investigate the effect of Uniform and Gaussian beam profiles on the enhancement of LED light penetration depth. The latter beam profiles were generated and compared using Flat and Aspherical lenses applied to the LED sources. In order to increase the signal to noise ratio, the lenses were also applied to the light detector. For performance analysis, two experiments were carried out by scanning the intra space of a liquid phantom by static and dynamic (pulsating) absorbers. Monte Carlo simulations were also carried out to be compared with the experiment. The results showed that Gaussian beam profile and in particular, Bi-Convex lenses applied to both source and detector leads to a greater light penetration depth in the liquid phantom close to that of a Laser source.

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Optical Fiber‐Based Optical Coherence Tomography

2021

Optical Fiber Sensing Technologies

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Catheter-Based Polarization Sensitive Optical Coherence Tomography Using Similar Mueller Matrix Method

Cited by 9 publications

References 30 publications

Estimation of Medium Depolarization Index with Noise Immunity in Catheter-Based PS-OCT toward Vascular Plaques Detection

Estimation of Medium Depolarization Index with Noise Immunity in Catheter-Based PS-OCT toward Vascular Plaques Detection

Enhancement of optical penetration depth of LED-based NIRS systems by comparing different beam profiles

Optical Fiber‐Based Optical Coherence Tomography

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