Catheter Ablation for Atrial Fibrillation in Patients With Left Ventricular Systolic Dysfunction. A Systematic Review and Meta-Analysis

Dagres, Nikolaos; Varounis, Christos; Gaspar, Thomas; Piorkowski, Christopher; Eitel, Charlotte; Iliodromitis, Efstathios K.; Lekakis, John; Flevari, Panayota; Simeonidou, Eftihia; Rallidis, Lοukianos S.; Tsougos, Elias; Hindricks, Gerhard; Sommer, Philipp; Anastasiou-Nana, Maria

doi:10.1016/j.cardfail.2011.07.009

Cited by 107 publications

(56 citation statements)

References 19 publications

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“…Several smaller trials suggest improved LV function after catheter ablation in HFrEF patients 185,226 -228,778,779 and reduced hospitalizations, 720,777 especially in patients without a previous myocardial infarction. 780 Larger trials are warranted to confirm these findings. Catheter ablation can be demanding in these patients.…”

Section: Ablation Of Atrial Fibrillation In Heart Failure Patientsmentioning

confidence: 51%

2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS

Kirchhof¹,

Benussi²,

Kotecha³

et al. 2016

Europace

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Section: Ablation Of Atrial Fibrillation In Heart Failure Patientsmentioning

confidence: 51%

2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS

Kirchhof¹,

Benussi²,

Kotecha³

et al. 2016

Europace

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3,697

1,414

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“…A number of studies, but not all, have reported a low stroke rate in patients who have undergone AF ablation when followed long term. 238,239,240,241,242 Although the results of these studies taken as a whole report a lower than expected stroke rate, these results can be considered preliminary data because many of these trials enrolled patients with a CHA 2 DS 2 -VASc score of <2, in whom stroke rates will be anticipated to be low. This reflects the fact that very few patients with a high stroke risk profile were followed long term after suspension of anticoagulation.…”

Section: Section 2: Definitions Mechanisms and Rationale For Af Ablmentioning

confidence: 88%

2012 HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: Recommendations for Patient Selection, Procedural Techniques, Patient Management and Follow-up, Definitions, Endpoints, and Research Trial Design

Calkins,

Kuck,

Cappato

et al. 2012

Heart Rhythm

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“…It is still not clear whether this subgroup would derive benefit from aggressive rate control or early rhythm control. 23,24 However, results from prospective studies 25 and a meta-analysis 26 suggest that when these patients undergo catheter ablation for AF, they have an objective improvement in functional class and systolic function.…”

Section: Discussionmentioning

confidence: 99%

Contemporary Trends of Hospitalization for Atrial Fibrillation in the United States, 2000 Through 2010

et al. 2014

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Background— Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. The associated morbidity and mortality make AF a major public health burden. Hospitalizations account for the majority of the economic cost burden associated with AF. The main objective of this study is to examine the trends of AF-related hospitalizations in the United States and to compare patient characteristics, outcomes, and comorbid diagnoses. Methods and Results— With the use of the Nationwide Inpatient Sample from 2000 through 2010, we identified AF-related hospitalizations using International Classification of Diseases, 9th Revision, Clinical Modification code 427.31 as the principal discharge diagnosis. Overall AF hospitalizations increased by 23% from 2000 to 2010, particularly in patients ≥65 years of age. The most frequent coexisting conditions were hypertension (60.0%), diabetes mellitus (21.5%), and chronic pulmonary disease (20.0%). Overall in-hospital mortality was 1%. The mortality rate was highest in the group of patients ≥80 years of age (1.9%) and in the group of patients with concomitant heart failure (8.2%). In-hospital mortality rate decreased significantly from 1.2% in 2000 to 0.9% in 2010 (29.2% decrease; P <0.001). Although there was no significant change in mean length of stay, mean cost of AF hospitalization increased significantly from $6410 in 2001 to $8439 in 2010 (24.0% increase; P <0.001). Conclusions— Hospitalization rates for AF have increased exponentially among US adults from 2000 to 2010. The proportion of comorbid chronic diseases has also increased significantly. The last decade has witnessed an overall decline in hospital mortality; however, the hospitalization cost has significantly increased.

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Catheter Ablation for Atrial Fibrillation in Patients With Left Ventricular Systolic Dysfunction. A Systematic Review and Meta-Analysis

Cited by 107 publications

References 19 publications

2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS

2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS

2012 HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: Recommendations for Patient Selection, Procedural Techniques, Patient Management and Follow-up, Definitions, Endpoints, and Research Trial Design

Contemporary Trends of Hospitalization for Atrial Fibrillation in the United States, 2000 Through 2010

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