Catastrophe Theory Applied to Neuropsychological Data: Nonlinear Effects of Depression on Financial Capacity in Amnestic Mild Cognitive Impairment and Dementia

Stamovlasis, Dimitrios; Giannouli, Vaitsa; Vaiopoulou, Julie; Tsolaki, Magda

doi:10.3390/e24081089

Cited by 5 publications

(2 citation statements)

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“…Of course, both of the groups of this sample are characterized as belonging to the ‘low stress’ category. An interesting new finding that is in contrast to previous literature [ 8 , 11 – 14 ] regarding financial capacity is that depressive symptomatology did not negatively influence LCPLTAS scores. This could be due to the low scores of depressive symptomatology as measured by GDS-15 in this sample that can not support a diagnosis of depression as was the case for the population in relevant prior studies [ 6 , 8 ].…”

Section: Discussioncontrasting

confidence: 95%

Stressful life events, general cognitive performance, and financial capacity in healthy older adults and Alzheimer’s disease patients

Giannouli

Tsolaki

2023

Neuropsychiatr

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Summary Background The influence of stressful life events on general cognition and for the first time on financial capacity performance of patients with a diagnosis of Alzheimer’s disease (AD) and in healthy controls (HC) is assessed. Methods A total of 268 participants (122 patients and 146 HCs with similar demographics) were examined with a number of neuropsychological tests, including Mini Mental State Examination (MMSE), Geriatric Depression Scale (GDS-15), and Legal Capacity for Property Law Transactions Assessment Scale (LCPLTAS) for measuring financial capacity. The life change unit (LCU) method was also used. Results HCs reported more stressful events than AD patients before the onset of the disease as the LCU load was higher for them (51.80 vs. 27.50), but in both groups the level of LCU load was far below 100, which is the threshold suggested for the induction of a psychosomatic disorder. The most frequently reported life event for AD patients was increased family arguments (n = 45/122), followed by increase in responsibilities (n = 32/122) and financial difficulties (n = 29/122), while the HC group reported problems within the family (n = 56/146), change in health status (n = 32/146), and a death of a beloved family member (n = 27/146). Regressions indicate no causal role for recent life events in the etiopathogenesis of AD, but an influence only of MMSE and diagnosis on financial capacity. Conclusions Stressful life events do not seem to be important in financial capacity and relevant vulnerability to financial exploitation for either HCs or AD patients; therefore clinicians should not consider them per se as a possible aggravating factor for financial deficits.

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Section: Discussioncontrasting

confidence: 95%

Stressful life events, general cognitive performance, and financial capacity in healthy older adults and Alzheimer’s disease patients

Giannouli

Tsolaki

2023

Neuropsychiatr

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“…In the fourth contribution, research by Stamovlasis et al [ 4 ], the authors investigate and propose a nonlinear model that might explain empirical data better than ordinary linear ones and elucidate the role of depression in a financial capacity. Financial incapacity is one of the cognitive deficits observed in amnestic mild cognitive impairment and dementia, while the combined interference of depression remains unexplored.…”

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confidence: 99%

Complexity Science in Human Change: Research, Models, Clinical Applications

Orsucci

Tschacher

2022

Entropy

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Vikriti, Agni and health: a preliminary mathematical model of Ayurvedic treatment

Fergusson,

Pekker,

Palakurthi

2023

IJCAM

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Ayurveda is a well-established form of alternative medicine. The terms Prakriti, Vikriti, Agni, and Koshta are well-known and their associations have been articulated in both the traditional literature of Ayurveda and by practicing Ayurvedic clinicians. These associations, while well understood and applied clinically, have not until recently been explored empirically. Correlational analysis has shown that these principles and processes of Ayurveda can be statistically observed in a large sample of patients. For example, Prakriti (the constitution of the body) and Vikriti (the current state of the body) are correlated to Agni (digestion) and Koshta (gut responsiveness), and results uniformly indicate that Vikriti is also associated to weight, body mass index, and diet, each an established cardiovascular disease risk factor. The present proof-of-concept case study takes these topics to the next stage of empirical investigation aimed at formulating an approach to bring Ayurvedic research into mainstream Life Sciences and complementary medicine. The principal challenge here is in a gap between the paradigms of modern Life Sciences and Ayurveda. We propose bridging this gap by formulating a minimal phenomenological nonlinear dynamics model to account for the critical role Agni plays in the health of Vikriti and for a threshold-type improvement in both Agni and Vikriti during the process of a six-month Ayurvedic treatment.

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Catastrophe Theory Applied to Neuropsychological Data: Nonlinear Effects of Depression on Financial Capacity in Amnestic Mild Cognitive Impairment and Dementia

Cited by 5 publications

References 59 publications

Stressful life events, general cognitive performance, and financial capacity in healthy older adults and Alzheimer’s disease patients

Stressful life events, general cognitive performance, and financial capacity in healthy older adults and Alzheimer’s disease patients

Complexity Science in Human Change: Research, Models, Clinical Applications

Vikriti, Agni and health: a preliminary mathematical model of Ayurvedic treatment

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