Cataract surgery in patients with uveitis

Rojas, Blanca; Zafirakis, Panayotis; Maleki, Arash

doi:10.1097/00055735-199702000-00003

Cited by 24 publications

(16 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Inflammatory squealae may develop at relatively predictable rates in eyes with a given inflammatory syndrome [4–7, 11–17]. However, these rates do vary markedly among syndromes.…”

Section: Review Of Current Literaturementioning

confidence: 99%

See 1 more Smart Citation

Cataract Surgery in Uveitis

Agrawal

Murthy

Ganesh³

et al. 2012

International Journal of Inflammation

View full text Add to dashboard Cite

Cataract surgery in uveitic eyes is often challenging and can result in intraoperative and postoperative complications. Most uveitic patients enjoy good vision despite potentially sight-threatening complications, including cataract development. In those patients who develop cataracts, successful surgery stems from educated patient selection, careful surgical technique, and aggressive preoperative and postoperative control of inflammation. With improved understanding of the disease processes, pre- and perioperative control of inflammation, modern surgical techniques, availability of biocompatible intraocular lens material and design, surgical experience in performing complicated cataract surgeries, and efficient management of postoperative complications have led to much better outcome. Preoperative factors include proper patient selection and counseling and preoperative control of inflammation. Meticulous and careful cataract surgery in uveitic cataract is essential in optimizing the postoperative outcome. Management of postoperative complications, especially inflammation and glaucoma, earlier rather than later, has also contributed to improved outcomes. This manuscript is review of the existing literature and highlights the management pearls in tackling complicated cataract based on medline search of literature and experience of the authors.

show abstract

“…Inflammatory squealae may develop at relatively predictable rates in eyes with a given inflammatory syndrome [4–7, 11–17]. However, these rates do vary markedly among syndromes.…”

Section: Review Of Current Literaturementioning

confidence: 99%

“…In many cases, the complications resulted in marked reduction of vision or even loss of the eye [ 11 ]. More recent publications have reported a considerable decrease in the incidence of intraoperative and postoperative complications during cataract extraction in uveitis [ 4 – 7 , 12 ].…”

Section: Historical Perspectivementioning

confidence: 99%

Cataract Surgery in Uveitis

Agrawal

Murthy

Ganesh³

et al. 2012

International Journal of Inflammation

View full text Add to dashboard Cite

show abstract

“…While the incidence of cataract varies according to the type of uveitis, it is potentially as high as 50% (Rojas 1997). Unlike the general public, people with uveitis often develop cataract at an earlier stage in life.…”

Section: Introductionmentioning

confidence: 99%

“…The use of a more flexible IOL has allowed for a smaller incision, avoidance of stitches, shorter surgical time, and speedier postoperative recovery. It is believed that utilization of a flexible IOL placed in the intact capsular bag results in less surgical trauma and surgically induced inflammation than alternative approaches (Rojas 1996). Current flexible materials include silicone and acrylic (Bellucci 2013).…”

Section: Introductionmentioning

confidence: 99%

Types of intraocular lenses for cataract surgery in eyes with uveitis

Leung

Lindsley

Kuo

2014

Cochrane Database of Systematic Reviews

View full text Add to dashboard Cite

Background Cataract formation often occurs in people with uveitis. It is unclear which intraocular lens (IOL) type is optimal for use in cataract surgery for eyes with uveitis. Objectives To summarize the effects of different IOLs on visual acuity, other visual outcomes, and quality of life in people with uveitis. Search methods We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (The Cochrane Library 2013, Issue 7), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE (January 1946 to August 2013), EMBASE (January 1980 to August 2013), Latin American and Caribbean Literature on Health Sciences (LILACS) (January 1982 to August 2013), the metaRegister of Controlled Trials (mRCT) (www.controlled-trials.com), ClinicalTrials.gov (www.clinicaltrials.gov) and the WHO International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en). We did not use any date or language restrictions in the electronic searches for trials. We last searched the electronic databases on 14 August 2013. We also performed forward and backward searching using the Science Citation Index and the reference lists of the included studies, respectively, in August 2013. Selection criteria We included randomized controlled trials (RCTs) comparing hydrophobic or hydrophilic acrylic, silicone, or poly(methyl methacrylate) (PMMA) IOLs with or without heparin-surface modification (HSM), with each other, or with no treatment in adults with uveitis, for any indication, undergoing cataract surgery. Data collection and analysis We used standard methodological procedures expected by The Cochrane Collaboration. Two review authors screened the search results and for included studies, assessed the risk of bias and extracted data independently. We contacted study investigators for additional information. We did not perform a meta-analysis due to variability in reporting and follow-up intervals for the primary and secondary outcomes of interest. Main results We included four RCTs involving 216 participants (range of 2 to 140 participants with uveitic cataract per trial) and comparing up to four types of IOLs. The largest study was an international study with centers in Brazil, Egypt, Finland, France, Japan, the Netherlands, Slovak Republic, Spain, and the USA; two studies were conducted in Germany and one in Saudi Arabia. There was substantial heterogeneity with respect to the ages of participants and etiologies of uveitis within and across studies. The length of follow-up among the studies ranged from 1 to 24 months after cataract surgery. The studies were at low risk of selection bias, but two of the four studies did not employ masking and only one study included all randomized participants in the final analyses. The funding source was disclosed by investigators of the largest study (professional society) and not reported by the other three. Due to heterogeneity in lens types evaluated and outcomes reported among the trials, we did not combine d...

show abstract

“…While the incidence rate of cataract varies according to the type of uveitis, it is potentially as high as 50% (Rojas 1997). Unlike the general public, uveitis patients often develop cataract at an earlier stage in life.…”

Section: Introductionmentioning

confidence: 99%