Cataract Formation and Cataract Extraction after Penetrating Keratoplasty

Martín, Timothy; Reed, John W.; Legault, Claudine; Oberfeld, Sheldon M.; Jacoby, Bradley G.; Yu, David D.; Dickens, Alan; Johnson, Holly P.

doi:10.1016/s0161-6420(13)31252-4

Cited by 57 publications

(33 citation statements)

References 17 publications

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“…Sequential surgery has been associated with increased graft endothelial cell count loss, and graft failure as high as 13-21%. 34,35,45,[48][49][50][51] However, improved surgical techniques and the use of intraocular viscoelastic agents may mean that secondary surgery can be performed with greater safety as suggested by a lower failure rate of 0-16% in more recent studies. 13,29,30,34,35,43,[49][50][51][52] Other authors have found no higher risk of graft failure from sequential surgery over triple procedure surgery, 13,28,35,46 with no significant difference in the percentage of endothelial cell loss 27,28 or increase in graft rejection episodes.…”

Section: Graft Survivalmentioning

confidence: 99%

The visual and refractive outcomes of combined and sequential penetrating keratoplasty, cataract extraction, and intraocular lens insertion

Nguyen

Mumford

Jones

et al. 2008

Eye

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Purpose The aim of this study was to investigate the visual and refractive outcome of combined penetrating keratoplasty, cataract extraction, and intraocular lens insertion (triple procedure) compared with cataract surgery following penetrating keratoplasty (sequential surgery). Methods Retrospective cohort study of 1256 first penetrating keratoplasty for Fuchs' dystrophy performed between April 1999 and December 2005. In all, 1202 triple and 54 sequential procedures were reviewed. At 1 year, refractive outcomes were available for 499 triple procedure and 26 sequential surgery eyes. At 2 years, data were available for 264 triple procedure and 10 sequential surgery eyes. At 1 and 2 years postoperatively, graft survival, best-corrected visual acuity (BCVA), spherical equivalent, and cylindrical error were recorded. v 2 -Tests were used to compare visual outcomes between the two groups.Results At 1 year after triple procedure surgery, 61% of eyes attained BCVA of X6/12, with 47% of eyes within±2 D of emmetropia. After sequential surgery, 59% achieved BCVA of X6/12 with 67% of eyes within±2 D of emmetropia ( ¼ 0.05). Mean spherical equivalent (MSE) at 1 and 2 years after triple procedure was þ 1.20 D (SD 5.45) and þ 0.15 D (SD 3.58), respectively. MSE following sequential surgery at 1 and 2 years was þ 0.08 D (SD 3.06) and À1.50 D (SD 3.14), respectively. Mean refractive cylinder after combined surgery was þ 4.16 D (SD 5.11) and þ 3.91 D (SD 2.79) at 1 and 2 years, respectively, compared with þ 3.65 D (SD 2.24) and þ 3.70 D (SD 2.06) after sequential surgery. In all, 29% of triple procedure and 27% sequential surgery eyes had an astigmatic error X5.0 D after 1 year (P ¼ 0.64), which increased to 34 and 30%, respectively, by the second year. The 5-year graft survival was 85% in both groups. There were no differences in graft survival, visual or refractive outcomes between triple procedure, and sequential surgery techniques. Conclusions This analysis provided no evidence of improved visual or refractive outcome after sequential surgery compared with triple procedure.

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Section: Graft Survivalmentioning

confidence: 99%

The visual and refractive outcomes of combined and sequential penetrating keratoplasty, cataract extraction, and intraocular lens insertion

Nguyen

Mumford

Jones

et al. 2008

Eye

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“…However, this incidence of cataract development in the patients required repeated transplantation was lower than the reported incidence after a single corneal transplantation (24-60%). [1][2][3] The incidence was also lower than the reported incidence of cataract in the population of 49 to 96-years-old and in the general population of various geographic areas. 7,8 The lower incidence of cataract in the regrafted patients in the current study may be explained by the lower age range.…”

Section: Discussionmentioning

confidence: 54%

“…In eight of them (50%) the corneal regraft remained clear, in seven of them the visual acuity improved from HM-20/200 to 20/100-20,/40 and in one, visual acuity remained poor due to cystoid macular oedema. In the other eight eyes (50%), the regrafts failed due to glaucoma (three eyes), immune rejection (2), suprachoroidal expulsive haemorrhage (1), regraft ulcer (1), and pseudophakic bullous keratopathy (1). All the eyes that underwent phacoemulsification or cum-capsular cataract extraction were complicated by bullous keratopathy.…”

Section: Surgical Management Of the Cataract Graft Clarity And Visumentioning

confidence: 99%

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Development and progression of cataract in patients required repeated corneal transplantation

Rumelt

Blum-Hareuveni

Bersudsky

et al. 2003

Eye

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Purpose To evaluate the incidence of cataract development in patients required repeated corneal transplantations, the types of cataract and the effect of cataract extraction on the corneal regrafts survival. Patients and MethodsThe charts of all the patients that underwent repeated corneal transplantation between 1985 and 1998 were reviewed for the development of cataract after the first or subsequent keratoplasties. In all, 80 patients underwent 122 repeated corneal transplantations, of which six underwent surgery in both eyes. The average follow-up period of all the patients with repeated keratoplasty was 89.5 months from the first keratoplasty.

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“…One of the factors to be blamed is the chronic use of steroids postoperatively 25 . Eyes with previous corneal grafts will benefit from being done by an experienced cataract surgeon, corneal graft decompensation is a possible complication of www.jors.js.iknito.com cataract surgery and the following precautions should be taken to reduce risk:…”

Section: B Special Considerations In Previous Corneal Graft (Pkp Damentioning

confidence: 99%

Must Know Cornea for Cataract Surgeons A Practical Guide

Gomaa

Farooqui

2017

Journal of Ophthalmology and Related Sciences

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Cataract Formation and Cataract Extraction after Penetrating Keratoplasty

Cited by 57 publications

References 17 publications

The visual and refractive outcomes of combined and sequential penetrating keratoplasty, cataract extraction, and intraocular lens insertion

The visual and refractive outcomes of combined and sequential penetrating keratoplasty, cataract extraction, and intraocular lens insertion

Development and progression of cataract in patients required repeated corneal transplantation

Must Know Cornea for Cataract Surgeons A Practical Guide

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