Cataract and quality of life in patients with glaucoma

Skalicky, Simon E.; Martin, Keith R; Fenwick, Eva; Crowston, Jonathan G; Goldberg, Ivan; McCluskey, Peter

doi:10.1111/ceo.12454

Cited by 26 publications

(28 citation statements)

References 42 publications

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“…Skalicky et al [8] demonstrate increased scores on the Glaucoma Activity Limitation-9 score, which they associate with QoL impairment, across all severities of glaucoma in patients with visually significant cataracts. They note that the degree of cataract was more predictive of impaired QoL than visual acuity itself in this population, suggesting the need for a broader metric for visual function in clinical practice such as the visual field index.…”

Section: Quality Of Life Improvement In Glaucoma Patientsmentioning

confidence: 98%

Glaucoma and cataract surgery

Shah

Law

Ahmed

2016

Current Opinion in Ophthalmology

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Although the challenges of performing cataract extraction on glaucoma patients exist, the potential benefit to these patients is substantial. With attention to pre- and perioperative surgical planning and intraoperative technique, as well as with awareness and potential utilization of novel devices and treatment strategies, cataract extraction offers a unique platform for anatomical and functional improvement in this increasingly common cohort of patients.

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Section: Quality Of Life Improvement In Glaucoma Patientsmentioning

confidence: 98%

Glaucoma and cataract surgery

Shah

Law

Ahmed

2016

Current Opinion in Ophthalmology

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“…Our finding that AMD has an additional impact on glaucoma patients' activity limitation is consistent with other studies exploring the role of ocular co‐morbidities in glaucoma patients. Visual impairment related to aphakia or cataract in glaucoma patients is associated with poorer GAL‐9 scores and other PRO measures assessing activity limitation compared with glaucoma patients without the additional ocular co‐morbidity . Likewise, several studies have demonstrated a link between ocular surface disease related to glaucoma therapy and reduced QoL in glaucoma patients .…”

Section: Discussionmentioning

confidence: 99%

“…Likewise, several studies have demonstrated a link between ocular surface disease related to glaucoma therapy and reduced QoL in glaucoma patients . Glaucoma and AMD each impact utility values; it is plausible that patients with both conditions have poorer preference‐based status than those with glaucoma alone.…”

Section: Discussionmentioning

confidence: 99%

“…A high person measure indicates greater activity limitation for the GAL‐9 . A detailed description of Rasch analysis can be found elsewhere …”

Section: Methodsmentioning

confidence: 99%

“…47 A detailed description of Rasch analysis can be found elsewhere. 39,47,48 Differential item functioning (DIF) is when a subgroup systematically responds differently to an item, despite similar underlying ability level. DIF was evaluated based on the presence or absence of AMD; this was used to assess relative ease or difficulty of each item by glaucoma patients without vs with AMD.…”

Section: Rasch Analysis Of the Glaucoma Activity Limitation-9mentioning

confidence: 99%

See 2 more Smart Citations

Impact of age‐related macular degeneration in patients with glaucoma: understanding the patients' perspective

Skalicky

Fenwick

Martin

et al. 2016

Clinical Exper Ophthalmology

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Factors Associated With Health-Related Quality of Life in Medically and Surgically Treated Patients With Glaucoma

Khanna

Holmes

2018

JAMA Ophthalmol

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IMPORTANCE Health-related quality of life (HRQOL) is often reduced with glaucoma, but associated factors are poorly understood. OBJECTIVE To determine factors associated with reduced HRQOL in medically and surgically treated patients with glaucoma. DESIGN, SETTING, AND PARTICIPANTS Prospective cohort study at a tertiary referral glaucoma practice, with 160 consecutive, prospectively enrolled medically or surgically treated adult patients with glaucoma. MAIN OUTCOME AND MEASURES All patients completed 2 HRQOL questionnaires (the 25-item National Eye Institute Visual Function Questionnaire and the Adult Strabismus-20 questionnaire [AS-20]). Thirty-six patients had undergone glaucoma drainage device surgery, 51 underwent trabeculectomy, and 73 were medically treated. Factors considered for association with HRQOL in multiple regression analyses were age, sex, best-eye and worst-eye mean deviation on Humphrey visual fields, treatment modality, best-eye and worst-eye visual acuity, and diplopia. RESULTS The mean (SD) age of participants was 69 (13) years, 63% were female, 97% were white, 93% were not Hispanic, and the mean deviation (SD) was −13 (10) dB. Reduced HRQOL was associated with worse diplopia (Diplopia Questionnaire score) on 6 subscales (range of partial r 2 [r p 2 ], 0.207-0.069). Reduced HRQOL was associated with lower best-eye mean deviation on 5 of 6 subscales (r p 2 range, 0.379-0.027), lower worst-eye mean deviation on 4 of 6 (r p 2 range, 0.242-0.046), treatment group on 3 of 6 (r p 2 range, 0.190-0.025), lower worst-eye visual acuity on 5 of 6 (r p 2 range, 0.063-0.025), lower best-eye visual acuity on 2 of 6 (r p 2 range, 0.032-0.017), and younger age on 2 of 6 (r p 2 range, 0.021-0.014). In adjusted analyses, glaucoma drainage device was associated with worse HRQOL in 3 AS-20 subscales compared with trabeculectomy and 2 AS-20 subscales compared with medical. Differences ranged from −14.7 to −7.4, with half the absolute magnitude of the full range of the 95% CI ranging from 9.2 to 5.7. CONCLUSIONS AND RELEVANCE Our findings support the assertion that reduced HRQOL is common in surgically and medically treated patients with glaucoma. Overall, poor HRQOL in patients with glaucoma is moderately associated with worse diplopia, lower mean deviation on visual field testing in either eye, poorer visual acuity in either eye, treatment type, and younger age. Previous glaucoma drainage device surgery was specifically associated with poorer HRQOL compared with trabeculectomy or medical treatment. Psychosocial effects of glaucoma drainage device should be considered when counseling patients with glaucoma.

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Cataract and quality of life in patients with glaucoma

Abstract: Background: To assess the impact of cataract on quality of life (QoL) for patients with glaucoma.

Cited by 26 publications

References 42 publications

Glaucoma and cataract surgery

Glaucoma and cataract surgery

Impact of age‐related macular degeneration in patients with glaucoma: understanding the patients' perspective

Factors Associated With Health-Related Quality of Life in Medically and Surgically Treated Patients With Glaucoma

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