Cataract after Busulphan Therapy

Akman, N; Avanoǧlu, Yildiz; Soysal, Tuba

doi:10.1159/000206064

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2018

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Cited by 6 publications

(4 citation statements)

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“…Busulfan has been indicated in cataract formation in numerous studies. 15-17 In our study population, however, busulfan was associated with a decreased incidence of cataract formation relative to TBI. A thorough literature search showed no studies linking cytarabine or thiotepa to cataract formation or protection.…”

Section: Discussionmentioning

confidence: 51%

Ocular complications in a young pediatric population following bone marrow transplantation

Hoehn

Calderwood²,

Gannon

et al. 2018

Journal of American Association for Pediatric Ophthalmology and

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Section: Discussionmentioning

confidence: 51%

Ocular complications in a young pediatric population following bone marrow transplantation

Hoehn

Calderwood²,

Gannon

et al. 2018

Journal of American Association for Pediatric Ophthalmology and

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“…Although busulphan given in massive doses causes posterior subcapsular cataracts in rats, this complication has been described only rarely in patients receiving busulphan. [11][12][13] Cataract extractions are planned for this patient.…”

Section: Discussionmentioning

confidence: 99%

Foscarnet as treatment for cytomegalovirus retinitis following bone marrow transplantation

Ganly

Arthur

Goldman

et al. 1988

Postgraduate Medical Journal

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“…The occurrence of cataract due to busulfan has been reported by laboratories [1, 2]and ophthalmologists after long-term administration of busulfan [3, 4, 5, 6, 7, 8, 9]. However, high doses of busulfan for a short time are given with bone marrow transplantation for myelocytic leukemia.…”

Section: Introductionmentioning

confidence: 99%

Cataract Induced by Short-Term Administration of Large Doses of Busulfan: A Case Report

Kaida¹,

Ogawa²,

Amemiya³

1999

Ophthalmologica

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Busulfan is a carcinostatic which is used for myelocytic leukemia. A 42-year-old Japanese woman given high doses of busulfan for a short time was referred to us because of decreased visual acuity and blurred vision in both eyes. She received 212 mg/day of busulfan for only 4 days. Ophthalmoscopic examination demonstrated a posterior polar subcapsular opacity of the lens in both eyes. Although the occurrence of cataract due to busulfan has been reported after long-term administration of busulfan, this is the first clinical case of cataract caused by high doses of busulfan for a short period. It is necessary to pay more attention to busulfan cataract.

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Cataract after Busulphan Therapy

Cited by 6 publications

References 1 publication

Ocular complications in a young pediatric population following bone marrow transplantation

Ocular complications in a young pediatric population following bone marrow transplantation

Foscarnet as treatment for cytomegalovirus retinitis following bone marrow transplantation

Cataract Induced by Short-Term Administration of Large Doses of Busulfan: A Case Report

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