Catalytic Reduction of Dinitriles

Catalytic Synthesis of Monomers for Heat-Resistant Polymers

“…First intermediate compound formed on the surface of the catalyst in the hydrogenation of nitriles and dinitriles is aldimine. The formation of the aminonitrile in the catalytic hydrogenation of aromatic dinitriles indicates sequential recovery of the nitrile groups [2,3,8,10].…”

“…The activity and selectivity of catalyst Ni-Nbsk under the catalytic synthesis of m-, p-xylylenediamine can be associated with a high degree of enrichment of the catalyst strongly bound by adsorbed hydrogen, which is 2-3 times higher than that of Nisk one [12]. The ammonia prevents reactive aldimines react with a primary amine, which are formed by reacting a Schiff base and further reaction with hydrogen passes to a secondary amine [3,7,10,11].…”

Stable and reusable Ni-based nanoparticles for general and selective hydrogenation of nitriles to amines

“…In addition, other nitriles with heterocyclic substituents such as quinoline, indole, pyrrole, thiazine, benzodioxol, benzodioxane, morpholine, tetrahydrofuran, as well as imidazole and triazole were selectively hydrogenated and produced the corresponding heterocyclic amines in up to 90% (Scheme 1, products [23][24][25][26][27][28][29][30][31][32][33][34].…”

“…26,27 In the chemical industry, hydrogenation of nitriles are frequently applied to prepare primary benzylic and aliphatic amines on a bulk scale. 9,10,14,[28][29][30][31][32][33][34][35][36][37][38][39][40][41] Since the rst nitrile hydrogenation of benzonitrile using heterogeneous Ni-catalysts reported already in 1905, 28 a plethora of materials and molecularly dened complexes based on precious and non-precious metals were developed for this transformation. 9,10,14,[29][30][31][32][33][34][35][36][37][38][39][40][41] Despite the many applications, most of these catalysts cannot be applied with high activity and selectivity for the hydrogenation of functionalized and structurally complex nitriles, specifically heterocyclic nitriles, which are valuable intermediates for agrochemicals and pharmaceuticals.…”

Reductive amination of oxygen-containing organic compounds

“…198,199 Data on the conditions and the mechanism of this reaction and various factors that influence its course have been described systematically. 200 The mechanisms of the formation of primary, secondary and tertiary amines were described in detail. In terms of their activity in this reaction, known catalysts can be arranged in the following sequence: Pt > Pd > Ni > Co > Fe > Cu.…”