Catalytic Light-Driven Strategy for Transforming Oximes to Carbonyls
Brandon White,
Travis Dudding
Abstract:Oxime and carbonyl functional groups serve as powerful chemical hubs for constructing complex synthetic targets and valuable molecular scaffolds. In furthering this value, we report a photopromoted catalytic deoximation protocol for converting oximes and their derivatives to carbonyl functional groups. This strategic approach benefits from the use of renewable light energy input and ambient air conditions, in addition to demonstrating good substrate scope, functional group tolerance, and product yields. In off… Show more
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