Catalyst‐Free Regioselective 1,2‐Diheterofunctionalization of Vinylferrocene
Patricia García‐Martínez,
Andrés Crespo,
Javier González
et al.
Abstract:In this study, we report a catalyst‐free aminohalogenation process applied to vinylferrocene, employing N‐halosuccinimides (NXS; X=Cl, Br, I) as dual nitrogen and halogen sources. This 1,2‐diheterofunctionalization reaction takes place with complete regioselectivity, wherein the terminal carbon atom of the vinyl group selectively reacts with the electrophilic halogenating reagent, resulting in the formation of a cationic intermediate, which is subsequently captured by the succinimide anion. The structure of th… Show more
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