Catalpol Content and Antioxidant Activities in Various Cultivars of Rehmannia glutinosa

Abstract

This study was to investigate catalpol content and antioxidant activities in five cultivars (Kokang, Suwon 10, Suwon 11, Jiwhang 1 and Korea) of Rehmannia Radix. Catalpol content was analysed by HPLC using C18 column (150×4.6 mm, 5 μm), 1% acetonitrile and a UV detector. The standard curve was found to be a linear regression of y＝0.0483x-0.0841 (R 2 =0.999). The catalpol content ranged from 85.2 mg/g to 144.9 mg/g, of which the Korea was the highest among cultivars. The total phenol content in Rehmannia Radix was 0.358～0.459 mg/g, of which the Korea was the highest among cultivars. The antioxidant activities determined by DPPH and hydroxyl radical scavenging activities were the highest in Korea with IC50 of 205.8 mg/g for DPPH radical scavenging activity and IC50 of 38.8 mg/g for hydroxyl radical scavenging activity. Based on these results, the Korea among Rehmannia Radix cultivars was suggested to be a potent medicinal plant material for antioxidant activities.

Traditional herbal prescription LASAP-C inhibits melanin synthesis in B16F10 melanoma cells and zebrafish

“…Although Rehmanniae Radix Crudus was the major component of LASAP-C in terms of quantity, phytochemicals from Scutellariae Radix were prominent as major peaks in the UPLC-MS study. The raw material of Rehmanniae Radix Crudus contained upto 77 % of water contents depends on cultivars [ 16 ] and many primary metabolites such as saccharides, vitamins, and amino acids [ 17 , 18 ]. The most common iridoidal glycoside of raw Rehmanniae Radix Crudus is catalpol and its content in the dried root has been reported as 0.142 to 0.225 % [ 16 ].…”

Improvement of the Field Productivity in Rehmannia glutinosa Libosch. Crops by Application of N, P and K Fertilizers and Plant Spacing

“…The dry root of Chinese foxglove was standardized to contain 5.4 mg gG 1 catalpol, which was determined by the same method of HPLC with the present study 41 . Few other studies also identified the catalpol contents; however, those levels are various due to different organs of the plant, development stages, cultivars and determination methods [42][43][44][45] . These studies appeared to not able to demonstrated the optimal fertilizer and cultivating establishments to achieve the acceptable field productivity of Chinese foxglove cultivation.…”

Physicochemical characteristics and fatty acid profiles of muscle tissues from Hanwoo steers fed a total mixed ration supplied with medicinal plant by-products

“…Zembayashi et al [ 21 ] confirmed that there was a correlation (y = 64.4–19.4x+ 3.54x 2 , r 2 = 0.79) between iron concentration and L* value (lightness), and suggested that beef color could be improved by a reduction in iron concentration of muscle. The total phenolics in Rehmanniae radix was 13.9 mg/g of which the Korea was the highest among cultivars [ 22 ]. The total phenolics and flavonoids of Angelica gigas nakai and Zingiber officinale roscoe were 2.23, 45.1, and 9.90, 11.1 mg/g of dry material, respectively [ 9 ].…”