Catabolism of germinant amino acids is required to prevent premature spore germination inBacillus subtilis
Iqra R. Kasu,
Octavio Reyes-Matte,
Alejandro Bonive-Boscan
et al.
Abstract:Spores ofBacillus subtilisgerminate in response to specific germinant molecules that are recognized by receptors in the spore envelope. Germinants signal to the dormant spore that the environment can support vegetative growth, so many germinants, such as alanine and valine, are also essential metabolites. As such, they are also required to build the spore. Here we show that these germinants cause premature germination if they are still present at the latter stages of spore formation and beyond, but thatB. subt… Show more
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