Casual associations of thyroid function with inflammatory bowel disease and the mediating role of cytokines
Shuyun Wu,
Jiazhi Yi,
Bin Wu
Abstract:BackgroundPrevious observational epidemiological studies have suggested a potential association between thyroid function and inflammatory bowel disease (IBD). However, the findings remain inconclusive, and whether this association is causal remains uncertain. The objective of this study is to investigate the causal association between thyroid function and IBD.MethodsGenome-wide association studies (GWAS) involving seven indicators of thyroid function, IBD, and 41 cytokines were analyzed. Bidirectional two-samp… Show more
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