2011
DOI: 10.5021/ad.2011.23.s2.s169
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Castleman's Disease with Cutaneous Involvement Manifestating as Multiple Violaceous Plaques on Entire Body

Abstract: Castleman's disease (CD) is an uncommon B-cell lymphoproliferative disorder characterized by lymph node hyperplasia with vascular proliferation. Cutaneous involvement in CD is rare. A 65-year-old man presented with a 7-year history of gradually developing multiple reddish to violaceous indurated plaques on the scalp, trunk, and legs. On physical examination, there were palpable enlarged cervical, axillary, and inguinal lymph nodes. Laboratory examination revealed anemia, thrombocytosis, hyperproteinemia, hypoa… Show more

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Cited by 17 publications
(16 citation statements)
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References 26 publications
(44 reference statements)
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“…Regarding epidemiologic features of published cases in kidney recipients (5/8), two patients had an explicit exposure to wound and agricultural environment. 2,4 Similar to our case, three of these five articles described a solitary lesion on lower limbs in the form of papule, plaque, or tumor, [3][4][5]…”
supporting
confidence: 78%
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“…Regarding epidemiologic features of published cases in kidney recipients (5/8), two patients had an explicit exposure to wound and agricultural environment. 2,4 Similar to our case, three of these five articles described a solitary lesion on lower limbs in the form of papule, plaque, or tumor, [3][4][5]…”
supporting
confidence: 78%
“…1 MCD is sometimes associated with skin involvement, and in such cases, the clinical and histologic features overlap with cutaneous and systemic plasmacytosis. 2,3 The skin lesions manifest as multiple erythematous to brownish plaques or nodules predominantly on the trunk and face. 2,4,5 The histologic finding of the cutaneous involvement was perivascular infiltration with plasma cells.…”
mentioning
confidence: 99%
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“…[ 8 ] Castleman's disease is histologically divided into three types: Hyaline vascular type or angiofollicular type, plasma cell (PC) type, and mixed type. [ 9 ]…”
Section: Introductionmentioning
confidence: 99%