Castleman disease mimicking a hepatic neoplasm

A Case of Castleman's Disease Mimicking a Hepatocellular Carcinoma: A Case Report and Review of Literature

“…7 Five more cases of localized Castleman's disease adjacent to the liver have been reported. [9][10][11][12][13][14][15][16][17] According to the case reports for localized Castleman's disease in the portal area, most cases had abdominal pain of variable intensity and duration (as in our case), whereas patients of localized Castleman's disease are commonly asymptomatic (Table 1). In addition, most of them were HV type (Table 1).…”

“…13,17 A 43 year-old female patient had a 13 cm diameter non-enhanced mass with calcification. 12 MRI of Castleman's diseases masses displays a hypodense mass in a T1-weighted image, and a hyperdense lesion in a T2-weighted image. 7,8 Images from 18-fluorodexyglucose PET demonstrates high standardized uptake values in Castleman's disease, but not as high as in active lymphoma.…”

“…12 However, needle biopsy is not recommended because an adequate tissue amount cannot be obtained, and biopsy increases the risk of bleeding or tumor seeding. 7,8 For hypervascular lesions in the liver, differential diagnosis may include focal nodular hyperplasia, adenoma, angiosarcoma, and HCC.…”

Castleman's Disease Mimicking Carotid Body Tumor

“…According to these publications the disease mimicks tumors of pancreas, liver, lungs, retroperitoneum, ovary, nerve sheaths, or lymph-nodes, but also sequester in mediastinal space, or malabsorption syndrome [8][9][10][11][12][13][14][15]. After a more detailed analysis it seems that the disease most often mimicks other processes characterized by the growth of tumor mass.…”