Casein phosphopeptide in cow's milk is strongly allergenic

Matsui, Teruaki; Naito, Michihiro; Kitamura, Katsumasa; Makino, Atsushi; Takasato, Yoshihiro; Sugiura, Shiro; Izumi, Hidehiko; Ito, Komei

doi:10.22541/au.163252091.16716154/v1

Cited by 1 publication

(2 citation statements)

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“…15 In a study conducted by Matsui, casein in CPP-ACP showed the epitome of allergy among patients. 16 The prevalence of casein allergy, estimated as ranging from 0.5% to 3%, begins at the age of 1. 17 CPP inhibited casein binds with IgE in a concentration-dependent manner and will contribute to the limitations of using CPP-ACP only in non-allergic patients.…”

Section: Introductionmentioning

confidence: 99%

“…17 CPP inhibited casein binds with IgE in a concentration-dependent manner and will contribute to the limitations of using CPP-ACP only in non-allergic patients. 16 The insufficiency and disadvantages that were found in CPP-ACP can be overcome by using natural sources of calcium that are affordable and not from milk products and their derivatives, one of which is T. granosa shell. It is supported by the prevalence of shellfish allergy, found to be 0-0.9%.…”

Section: Introductionmentioning

confidence: 99%

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Tegillarca granosa shell combination with Vitis vinifera and fluoride in decreasing enamel microporosity

Setiawan,

Tinisia,

Rahim

et al. 2024

Dent. J.

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Background: White spot lesion is a demineralization process indicated by the increased of enamel microporosity. A tegillarca granosa shell contains 98.7% calcium and Vitis vinifera contains phytochemical compounds with fluoride, which has a potential to stimulate remineralization. Purpose: To analyze the Tegillarca granosa shell combination with Vitis vinifera and fluoride in decreasing enamel microporosity. Methods: The cream was prepared by combining 10% and 20% Tegillarca granosa shell with 10 grams of Vitis vinifera extract and 100 mg of fluoride. The cream was tested beforehand for viscocity and pH. Furthermore, 16 premolars were etched and divided into four groups. Group 1 was smeared with placebo (negative control) and Group 2 was smeared with casein phosphopeptide-amorphous calcium phosphate (positive control). The other groups were smeared with cream 10% (Group 3) and 20% (Group 4) Tegillarca granosa shell combination with Vitis vinifera and fluoride. Teeth were treated three times a day for 30 minutes and soaked in artificial saliva. After 14 days, the enamel microporosity was carried out using a scanning electron microscope. The data was analyzed with one-way analysis of variance (ANOVA) test followed by post-hoc least significant difference (LSD). Results: The enamel microporosity showed significant difference between Group 1 and the other groups. There was no significant difference between Groups 2, 3, and 4 (p<0.05). Although there was no significant difference between Group 3 and 4, the lowest one was in Group 4 (p>0.05). Conclusion: The cream, prepared by combining Tegillarca granosa shell with Vitis vinifera and fluoride, is effective in decreasing the enamel microporosity.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%