Caseating granulomas of the heart

Cardiac Tuberculoma of the Right Atrium

“…Most of the single or multiple well‐circumscribed cardiac tuberculomas are located in the right heart chambers, particularly in the right atrium. They are usually sharply demarcated from the surrounding parenchyma 7‐9 . Our case showed extension of the mass to the tricuspid valve septal leaflet resulting in severe obstruction of the right ventricular inflow tract.…”

Case report: Myocardial tuberculosis-MRI

“…[3] Most cases occur secondary to hematogeneous spread from a remote tuberculous focus, lymphatic spread from mediastinal nodes, or direct spread from the adjacent pericardium. [24]…”

“…Pathologically, there are three patterns of involvement;[4] these are as follows: (i) miliary tuberculosis, with the heart being just one of the many organs involved; (ii) diffuse infiltrating interstitial disease; and (iii) caseating nodular disease (tuberculoma). The miliary form is by far the commonest; tuberculomas are much rarer.…”

“…The miliary form is by far the commonest; tuberculomas are much rarer. [4] The lesions may involve the atria, the ventricles, or the interventricular septum. [5] Tuberculosis may lead to heart block[6] or other abnormal rhythms, as well as myocardial rupture.…”

Obstruction of the right ventricular outflow tract caused by a tuberculoma in a patient with ventricular septal defect and aneurysm of the membranous septum

“…Tuberculomas of the heart are isolated or multiple firm nodules, 2-70 mm in diameter, composed histologically of multiple small focuses of giant cells with central caseation. 4 They are very rare tumours, and only one case was found in a series of 20 000 autopsies. 5 There are few reported cases of tuberculomas of the heart, most of which were diagnosed at necropsy.…”