Case Study: Major Duodenal Papilla Cancer Complicated by Acute Paracancrotic Necrotizing Pancreatitis

Abstract

The given paper describes a case of treating adenocarcinoma of the papilla of Vater diagnosed as the cause after an episode of acute pancreatitis. The etiology of aсute pancreatitis was considered idiopathic until the onset of complaints caused by tumor growth. The volume of radical surgery has changed intraoperatively due to the detection of infected limited necrotic clusters, didn’t diagnosed both laboratory and instrumentally. Pathomorphological conclusion: considering clinical data, low-grade (G3) adenocarcinoma of the major duodenal papilla, which developed from pre-existing tubular villous adenoma of the duodenum or intraampullary papillary neoplasia (IAPN). Predicting the early detection of MNPs after AP episode requires further research by improving imaging techniques, introducing new non-invasive techniques and investigating circulating biomarkers. The scope of surgery for patients with clinically significant complications of tumor growth and identified competing diagnosis at the target site should be individually decided and weighed. Infected pancreatitis in the late stages requires careful diagnosis.

Endoscopic treatment of a patient with duodenal major papilla adenoma and ansa pancreatica

“…This patient had a major duodenal papilla adenoma at the same time. Acute pancreatitis owing to the periampullary tumor has been reported in previous literature and the obstruction of the major papilla was supposed to be the reason 6 . But in this case, no dilation of the pancreatic duct due to obstruction was identified, and she had not experienced an episode of acute pancreatitis ever since ERCP.…”

“…Acute pancreatitis owing to the periampullary tumor has been reported in previous literature and the obstruction of the major papilla was supposed to be the reason. 6 But in this case, no dilation of the pancreatic duct due to obstruction was identified, and she had not experienced an episode of acute pancreatitis ever since ERCP. Thus, we considered that ansa pancreatica mainly accounted for her recurrent pancreatitis.…”