2019
DOI: 10.1155/2019/2398342
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Case Series of Recurring Spontaneous Closure of Macular Hole

Abstract: Macular hole can undergo spontaneous reopening and reclosure. This is a retrospective review of three patients who had spontaneous reopening and reclosure of previously spontaneously closed macular hole documented by optical coherence tomography. We report the first case of nivolumab-uveitis-associated macular hole formation. The authors hypothesize that cystoid macular edema (CME) might alter the integrity of foveal tissues or conversely the orientation of the macular hole edges and play a role in formation a… Show more

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Cited by 9 publications
(9 citation statements)
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“…Management of different ocular disorders has been revolutionized due to the tremendous advances in OCT technology [24,25,29]. This cohort of 44 eyes with a mean follow-up duration of 3 ± 0.6 months after the last session of the PRP represented the short-term longitudinal changes in the CMT and SFCT using SS-OCT.…”
Section: Discussionmentioning
confidence: 99%
“…Management of different ocular disorders has been revolutionized due to the tremendous advances in OCT technology [24,25,29]. This cohort of 44 eyes with a mean follow-up duration of 3 ± 0.6 months after the last session of the PRP represented the short-term longitudinal changes in the CMT and SFCT using SS-OCT.…”
Section: Discussionmentioning
confidence: 99%
“… 11 The current study was not designed to evaluate this natural history question. Although spontaneous closure of small MHs has been demonstrated, 12 and some providers recommend observation of early, small MHs, this was not the usual practice of the current investigators.…”
Section: Discussionmentioning
confidence: 92%
“…9,10 Intraretinal edema might facilitate spontaneous MH closure by reapproximating the hole edges through physical expansion, and recurrent macular edema, as is associated with CRVO and visible in Figure 1F, might have exercised this effect. 11 The ERM was also visible in Figure 1F, and centripetal contraction of this thin ERM after the next intravitreal RBZ could have released the mechanical stress on the retina, allowing for approximation of MH edges and hole closure. 10 To conclude, this case reinforces the importance of careful evaluation of the vitreoretinal interface before and during intravitreal pharmacotherapy for RVO.…”
Section: Discussionmentioning
confidence: 97%