Case Series of Acute Meconium Peritonitis Secondary to Perforation of the Ileum in the Antepartum Period

Piccioni, Maria Grazia; Merlino, Lucia; D’Ovidio, Giulia; Prete, Federica Del; Galli, V.; Petrivelli, Lucia; Vena, Flaminia; D’Ambrosio, Valentina; Giancotti, Antonella; Brunelli, Roberto

doi:10.3390/jcm11237127

Cited by 2 publications

(2 citation statements)

References 18 publications

(19 reference statements)

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“…The finding of echogenic foci in the abdomen has little postnatal significance. [19][20][21] Finally, regarding the association between hyperechoic intestine and cystic fibrosis or aneuploidy, the degree of echogenicity appears to play a role. Intestinal echogenic grades 2 and 3 (according to Slotnick et al classification) is associated with a high positive rate of parental carrier testing for cystic fibrosis (CF) and amniocentesis.…”

Section: Prognosismentioning

confidence: 99%

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Hyperechogenic fetal bowel: Current evidence‐based prenatal diagnosis and management

Vena

Bartolone

et al. 2023

J of Clinical Ultrasound

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Echogenic fetal bowel (EB) is a prenatal ultrasound finding (0.2%–1.4% of all pregnancies) defined as bowel of similar or greater echogenicity than surrounding bone. In fact, the ultrasound assessment is strongly subjective with inter‐observer variability. The pathophysiology depends on the underlying condition, apparently related with meconium stasis and hypercellularity. It is often an isolated finding, with possible association with other structural anomalies. About the origin, it was observed in fetuses with cystic fibrosis, congenital infections, thalassemia, intraamniotic bleeding, fetal growth restriction. Fetuses with EB are at increased risk of adverse perinatal outcome, such as intrauterine growth restriction, placental dysfunction and perinatal death, highlighting the need for a thorough antenatal management and post‐natal follow‐up. It seems to be associated with a plenty of conditions, such as a poor fetal outcome, fetal growth restriction and placental dysfunction. Therefore management requires a multidisciplinary approach with different specialties' involvement and the prognosis is influenced by the underlying pathophysiology. In this complex scenario, the present review aims to define the clinical pathway which should be offered to pregnant women in case of finding of fetal EB ultrasound marker, to rule out any suspected pathological cause.

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Section: Prognosismentioning

confidence: 99%

“…However surgical outcomes are good. The finding of echogenic foci in the abdomen has little postnatal significance 19–21 …”

Section: Introductionmentioning

confidence: 99%

Hyperechogenic fetal bowel: Current evidence‐based prenatal diagnosis and management

Vena

Bartolone

et al. 2023

J of Clinical Ultrasound

Self Cite

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Does prenatal diagnosis of meconium peritonitis have the better recovery? A single-center over 10 years of experience

Li,

Lu,

Wang

et al. 2024

Pediatr Surg Int

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Objective: To evaluate whether infants with prenatal diagnosis of meconium peritonitis (MP) have a poorer prognosis. Methods: A retrospective analysis of data from infants treated with surgery from January 2008 to December 2020 was conducted. The patients were divided into prenatal diagnosis group and postnatal diagnosis group based on the timing of diagnosis. The intraoperative and postoperative parameters of the two groups of patients were compared. Results: A total of 71 cases of MP were included in the study, with 48 cases in the prenatal diagnosis group and 23 cases in the postnatal diagnosis group. The comparison of preoperative indicators between the two groups of patients showed no statistically signi cant differences in baseline (P>0.05). Intraoperative indicators, including blood loss, anastomosis, retained intestinal tube length, and excised intestinal tube length, showed no statistically signi cant differences between the two groups (P>0.05). However, the postnatal diagnosis group had a signi cantly shorter operation time than the prenatal diagnosis group (P<0.05). Postoperative indicators, including fasting time, albumin usage, complications, and abandonment or mortality rate (P>0.05). Nevertheless, the postnatal diagnosis group exhibited signi cantly shorter hospital stay and time to rst bowel movement compared to the prenatal diagnosis group (P<0.05). Conclusion: Prenatal diagnosis of meconium peritonitis is associated with higher surgical di culty, longer hospital stay and delayed intestinal function recovery. However, there is no evidence of higher mortality rates or more complications compared to infants diagnosed postnatally, and there is no signi cant difference in long-term prognosis.

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Case Series of Acute Meconium Peritonitis Secondary to Perforation of the Ileum in the Antepartum Period

Cited by 2 publications

References 18 publications

Hyperechogenic fetal bowel: Current evidence‐based prenatal diagnosis and management

Hyperechogenic fetal bowel: Current evidence‐based prenatal diagnosis and management

Does prenatal diagnosis of meconium peritonitis have the better recovery? A single-center over 10 years of experience

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