Case reports and case series from had significant impact on medical literature

Case Reports: Contribution to Clinical Practice, Scholarly Education, and Scientific Knowledge

“…Case reports in a high impact journal can have considerable influence on the literature and research. For example, Albrecht J et al 2005 [8] identified 64 case reports and 39 small case series published in The Lancet between January 1996 and June 1997. Of the 64 reports 11 (17%) were followed by clinical trials, 4 (6%) of which were found in the Register of Current Controlled Clinical Trials.…”

Case Reports: Yes or No

“…A recent study in The Lancet concluded that eleven (17%) of the case reports published in The Lancet led to clinical trials. 4 …”

Case Reports: More than Anectodal Evidence

“…Recently, some authors demonstrated that case reports and case series can have substantial impact on the literature, and for many treatments they are the only available evidence. Therefore they suggested that a guideline for case reporting should be developed to improve their quality [3].…”