Case Report: Pazopanib-induced acute coronary syndrome
Adithya K. Yadalam,
William M. Schultz,
Chanhee Han
et al.
Abstract:IntroductionPazopanib is a tyrosine kinase inhibitor approved for the treatment of metastatic renal cell carcinoma and advanced soft-tissue sarcoma that functions by inhibiting vascular endothelial growth factor receptors. Although the package insert and current cardio-oncology guidelines indicate a risk of acute coronary syndrome (ACS) associated with pazopanib, the causative role of pazopanib in arterial thrombosis is unclear due to a lack of focused coronary disease evaluation in oncological clinical trials… Show more
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