Case Report of Percutaneous Tract Seeding of Renal Pelvic Tumor: 8-Year Journey

Yohannes, Paulos

doi:10.1089/cren.2016.0106

Cited by 2 publications

(2 citation statements)

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“…To date, there are a total of 25 reported cases on tumor seeding along the percutaneous renal mass biopsy tract, from several case reports and one case series [8,[11][12][13][14][15][16]. Of these, PRCC (15 cases) was the most commonly encountered pathologic subtype.…”

Section: Discussionmentioning

confidence: 99%

“…Historically, the rate of needle tract tumor seeding in renal biopsy was estimated to be as low as 0.01 % by Smith in 1991, and Herts and Baker in 1995 [9,10]. To date, only a handful of case reports and a small case series have been published [8,[11][12][13][14][15][16]. However, the frequency and clinical significance of biopsy-associated tumor seeding remains largely controversial due at least in part to lack of systemic review, histological analysis and follow up data in early studies [9,10,17].…”

Section: Introductionmentioning

confidence: 99%

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Needle tract seeding in renal tumor biopsies: experience from a single institution

Zhou

Murugan

et al. 2021

Diagn Pathol

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Background Percutaneous needle biopsy of renal masses has been increasingly utilized to aid the diagnosis and guide management. It is generally considered as a safe procedure. However, tumor seeding along the needle tract, one of the complications, theoretically poses potential risk of tumor spread by seeded malignant cells. Prior studies on the frequency of needle tract seeding in renal tumor biopsies are limited and clinical significance of biopsy-associated tumor seeding remains largely controversial. Methods Here we investigated the frequencies of biopsy needle tract tumor seeding at our institution by reviewing the histology of renal cell carcinoma nephrectomy specimens with a prior biopsy within the last seventeen years. Biopsy site changes were recognized as a combination of foreign body reaction, hemosiderin deposition, fibrosis and fat necrosis. The histologic evidence of needle tract tumor seeding was identified as clusters of tumor cells embedded in perinephric tissue spatially associated with the biopsy site. In addition, association between parameters of biopsy techniques and tumor seeding were investigated. Results We observed needle tract tumor seeding to perinephric tissue in six out of ninety-eight (6 %) renal cell carcinoma cases including clear cell renal cell carcinoma, papillary renal cell carcinoma, chromophobe, and clear cell papillary renal cell carcinoma. The needle tract tumor seeding was exclusively observed in papillary renal cell carcinomas (6/28, 21 %) that were unifocal, small-sized (≤ 4 cm), confined to the kidney and had type 1 features. No recurrence or metastasis was observed in the papillary renal cell carcinoma cases with tumor seeding or the stage-matched cases without tumor seeding. Conclusions Our study demonstrated a higher than reported frequency of needle tract tumor seeding. Effective communication between pathologists and clinicians as well as documentation of tumor seeding is recommended. Further studies with a larger patient cohort and longer follow up to evaluate the impact of needle tract tumor seeding on long term prognosis are needed. This may also help reach a consensus on appropriate pathologic staging of renal cell carcinoma when the only site of perinephric fat invasion is within a biopsy needle tract.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Needle tract seeding in renal tumor biopsies: experience from a single institution

Zhou

Murugan

et al. 2021

Diagn Pathol

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Cutaneous seeding of transitional cell carcinoma of the urinary bladder after placement of a subcutaneous ureteral bypass device in a dog with bilateral ureteral obstruction

Merickel

Lawrence

Young

et al. 2021

javma

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CASE DESCRIPTION A 12-year-old spayed female Jack Russell Terrier was presented with pollakiuria and stranguria. CLINICAL FINDINGS Transitional cell carcinoma (TCC) of the urinary bladder trigone and urethra was diagnosed via CT, cystoscopic, and histologic examinations. Azotemia developed 2 weeks following diagnosis, secondary to bilateral ureteral obstruction. TREATMENT AND OUTCOME Percutaneous antegrade ureteral stenting was unsuccessful; therefore, a subcutaneous ureteral bypass (SUB) device with 2 nephrostomy and 1 cystostomy catheters was surgically placed. Two months following placement of the SUB device, the dog developed a firm, multilobulated cutaneous mass at the site of the subcutaneous access port of the SUB device. Results of cytologic examination of cells aspirated from the mass were consistent with TCC. Within 1 month of confirmation of TCC of the cutaneous mass, the mass was ulcerated and infected, and the dog was euthanized because of signs of pain and perceived poor quality of life. CLINICAL RELEVANCE Seeding of neoplastic cells is a known complication of needle aspiration or biopsy or surgery in people and dogs with carcinomas. The occurrence of TCC at the SUB port site suggested caution with the placement of a SUB device in dogs with obstructive TCC.

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Case Report of Percutaneous Tract Seeding of Renal Pelvic Tumor: 8-Year Journey

Cited by 2 publications

References 4 publications

Needle tract seeding in renal tumor biopsies: experience from a single institution

Needle tract seeding in renal tumor biopsies: experience from a single institution

Cutaneous seeding of transitional cell carcinoma of the urinary bladder after placement of a subcutaneous ureteral bypass device in a dog with bilateral ureteral obstruction

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