Case report of maxillary osteosarcoma with up-to date review

Soufflet, Elise; Thibaut, F

doi:10.1051/mbcb/2020008

Cited by 3 publications

(5 citation statements)

References 14 publications

(21 reference statements)

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“…In our case report, the patient was a 65-year-old man. In contrast, the case report of French authors described a case of osteosarcoma of the maxilla of a 17-year-old patient [1,9].…”

Section: Discussionmentioning

confidence: 92%

“…Unfortunately, tooth extraction occurs in two-thirds of cases [5]. The most common complaint is painless swelling, which can sometimes be associated with dysesthesia and/or limited mouth opening [1]. These lesions in the maxilla may mimic a periapical lesion of endodontic (dental) origin, and the differential diagnosis is mandatory [6].…”

Section: Discussionmentioning

confidence: 99%

“…Compared to the clinical presentation of osteosarcomas of the long bones, osteosarcomas of the jaw occcur in an older patient population (30-50 years). The mandible is more often affected than the maxilla [1].…”

Section: Introductionmentioning

confidence: 99%

“…Laskar et al evaluated the efficacy and toxicity of dose-escalated IGI modulated radiation therapy in osteosarcoma. The five-year local control improved the survival in 66% [1,13].…”

mentioning

confidence: 96%

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Highly Aggressive Osteosarcoma of the Ethmoids and Maxillary Sinus-A Case of Successful Surgery and Proton Beam Radiotherapy in a 65-Year-Old Man

et al. 2022

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Sarcomas in the head and neck area are rare diseases with an incidence of under 1% of all head and neck malignant tumours. Osteosarcomas or osteogenic sarcomas consist of neoplastic cells that produce osteoid bone or immature bone. Sarcomas develop more in the mandible than the maxilla. The exact diagnosis of different types of sarcomas is based on the immunohistochemical investigation. These rare tumours are of mesenchymal origin; osteosarcomas and chondrosarcomas are the most common types—Ewing’s sarcomas. The use of proton beam radiotherapy in the treatment of osteosarcoma of the maxilla is rarely reported in the literature. We present a case of successfully treated (surgery and proton beam radiotherapy) poorly differentiated highly aggressive osteosarcoma in the ethmoids and maxillary sinus and morbidity after the treatment. We were presented with a case of a 65-year-old man with anaesthesia and palsy of the right face. The stomatology department performed the extraction of a tooth. One month later, the wound was still open. The histology showed an osteogenic sarcoma in the area of the wound. The oncologist and maxillofacial surgeons in a catchment hospital recommended a nonsurgical approach. Hence, we performed a radical maxillectomy and ethmoidectomy, after which we continued with proton bean radiotherapy. The patient is now five years after therapy without signs of sarcoma; however, he has blindness in the right eye and reduced vision in the left eye, as well as gliosis of the brain, vertigo, tinnitus, trismus, and ancylostomiases. Head and neck osteosarcomas treatment is considered a complex multidisciplinary task. It is currently argued that there is no clear therapeutic protocol for successful treatment. Innovations in treatment modalities such as proton beam radiotherapy appear to have potential, although their effects on long-term morbidity and survival outcomes are still undetermined. We present a rare case report of an osteosarcoma of the maxilla involving an innovative, successful treatment procedure combining surgical excision followed by proton beam radiotherapy. This treatment approach may enable maximum tumour control. This protocol has not been adequately described in the world literature for this diagnosis.

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“…In our case report, the patient was a 65-year-old man. In contrast, the case report of French authors described a case of osteosarcoma of the maxilla of a 17-year-old patient [1,9].…”

Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…Laskar et al evaluated the efficacy and toxicity of dose-escalated IGI modulated radiation therapy in osteosarcoma. The five-year local control improved the survival in 66% [1,13].…”

mentioning

confidence: 96%

See 2 more Smart Citations

Highly Aggressive Osteosarcoma of the Ethmoids and Maxillary Sinus-A Case of Successful Surgery and Proton Beam Radiotherapy in a 65-Year-Old Man

et al. 2022

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“…In the orofacial region, the mandible is more commonly affected than the maxilla with a ratio of 1.5:1, with males showing a predilection for occurrence in the mandible and females in the maxilla. 8,9 In mandible, the body is most commonly involved followed by angle, symphysis, ascending ramus, and the antrum. 4 This article reports a case of OS in the posterior maxilla.…”

Section: Introductionmentioning

confidence: 99%

Osteosarcoma of Maxilla - An Unusual Entity: Case Report and Review of Literature

HAMEED,

ANTO,

VENGAL

et al. 2023

Cumhuriyet Dental Journal

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Malignant bone tumors are rare malignancies of which osteosarcomas are the most common considering bone marrow tumors are excluded. They account for approximately 6-10% of jaw lesions and affect the mandible more often than the maxilla. A review of literature shows there are rare cases of osteosarcomas reported in the maxilla; however, given the lack of specific signs and a diverse range of radiographic features, the diagnosis is often difficult and requires a multidisciplinary discussion. This is the case report of a 56-year-old female presenting a well-defined, dome-shaped firm swelling with radiographic features of extensive destruction of the buccal cortical bone in the maxillary right posterior region. Early diagnosis helped in the better prognosis of the patient. She is undergoing regular follow-ups to ensure no recurrences of this aggressive lesion. Osteosarcoma of the jaw is difficult to diagnose and manage due to the high frequency of errors in biopsy results, the few specific radiological characteristics, and difficulties in appropriate resections because of the proximity to vital structures. Through the years, the survival of patients has greatly improved, due to an aggressive systemic approach and refined surgical and reconstructive techniques. However, for purposes of management, emphasis should be laid on the aggressiveness of this lesion which warrants an early identification and diagnosis of the lesion followed by prompt treatment.

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A Rare Case Report of Osteosarcoma of Maxilla with Double Free-Flap Reconstruction

Dabas,

Menon,

Ranjan

et al. 2023

Indian J Surg Oncol

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Case report of maxillary osteosarcoma with up-to date review

Cited by 3 publications

References 14 publications

Highly Aggressive Osteosarcoma of the Ethmoids and Maxillary Sinus-A Case of Successful Surgery and Proton Beam Radiotherapy in a 65-Year-Old Man

Highly Aggressive Osteosarcoma of the Ethmoids and Maxillary Sinus-A Case of Successful Surgery and Proton Beam Radiotherapy in a 65-Year-Old Man

Osteosarcoma of Maxilla - An Unusual Entity: Case Report and Review of Literature

A Rare Case Report of Osteosarcoma of Maxilla with Double Free-Flap Reconstruction

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