Case report of bilateral inflammatory breast cancer

Masannat, Yazan; Peter, MB; Turton, Philip; Shaaban, Abeer M.

doi:10.1111/j.1365-2354.2009.01075.x

Cited by 5 publications

(5 citation statements)

References 13 publications

(18 reference statements)

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“…Two of these cases involved HER2-positive breast cancer, and one involved TNBC. One case of bilateral IBC with bilateral carcinomatous pleurisy ( 14 ) and two cases of metachronous IBC found within one year after the first operation for unilateral IBC have been reported ( 15 , 16 ). The factors involved in the pathogenesis and progression of bilateral IBC remain unclear.…”

Section: Discussionmentioning

confidence: 99%

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Bilateral Inflammatory Breast Cancer That Developed Two Years after Treatment for Triple-negative Breast Cancer

et al. 2022

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A 66-year-old woman underwent partial mastectomy and a sentinel lymph node biopsy for left breast cancer; the pathological diagnosis was invasive ductal carcinoma (pT1aN0, pStage I, triple-negative subtype). Postoperative radiotherapy was performed. Two years later, she developed redness and induration at both breasts. The diagnosis was bilateral inflammatory breast cancer. After four cycles of dose-dense epirubicin and cyclophosphamide followed by 12 weekly paclitaxel cycles, bilateral total mastectomy and axillary lymph node dissection were performed. At the one-year follow-up after undergoing operation and radiotherapy, she remained alive without recurrence. Dose-dense treatment regimens may help patients achieve complete resection without short-term recurrence.

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Section: Discussionmentioning

confidence: 99%

“…Compared to patients with unilateral breast cancer, those with bilateral breast cancer are younger and have smaller and earlier-stage tumors at the diagnosis. A few case reports of bilateral IBC have been published (14)(15)(16). Two of these cases involved HER2-positive breast cancer, and one involved TNBC.…”

Section: Discussionmentioning

confidence: 99%

Bilateral Inflammatory Breast Cancer That Developed Two Years after Treatment for Triple-negative Breast Cancer

et al. 2022

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“…In rare cases, thyroid dermopathy (almost always associated with ophthalmopathy) can present as "peau d' orange" [10] in different areas of the skin in both sexes. Moreover, bilateral inflammatory breast cancer is a very rare entity [11] but it should be ruled out in all cases because of poor prognosis and the necessity of immediate systemic treatment. Although there is no consensus on the definition of breast edema and standardized assessment criteria, common criteria for breast edema found in the literature are an increased volume of the breast, peau d'orange, heaviness of the breast and redness of the skin [12], all included in our case report.…”

Section: Discussionmentioning

confidence: 99%

Bilateral Breast Edema: Case Report and Review of the Literature

Vouxinou

Iatrakis

Zervoudis

et al. 2020

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Both benign and malignant conditions related to regional or systemic disorders could be included in the differential diagnosis of bilateral breast edema. Some of them are often unilateral, including stromal infiltration and lymphatic obstruction presented in “peau d’ orange”, which is the usual presentation of breast cancer. However, the term “idiopathic” could be included in the spectrum of diagnoses. Here, we present a woman of 78 years old who came into our breast unit with a bilateral, painless edema of the breasts (appeared one month ago). Clinical examination revealed that both breasts were swollen with widespread erythema and the appearance of an orange peel/“peau d’ orange”. On palpation, the breasts were not sensitive, and no tumor was palpable. However, clinically palpable lymph nodes were found in both axillas. Her temperature was normal. The breast edema could not be explained from her medical history nor the medications taken. Breast ultrasound, Mammography and Magnetic Resonance Imaging were non-conclusive (BI-RADS 0) and bilateral core biopsy was negative for cancer. Anti-inflammatory plus antibiotic therapy was prescribed for 10 days and at the end of treatment, regional redness and edema were disappeared and reduced, respectively. Total recovery was found one month after the initial findings. It can be concluded that bilateral breast edema is correlated to regional or systemic conditions or it is presented as an “idiopathic” disorder of unknown etiology.

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“…As such, the differential diagnosis includes an inflammatory breast cancer which is usually unilateral and associated with erythema and axillary lymphadenopathies. 3,4 Secondary inflammatory involvement of the breasts from an extramammary primary such as ovarian or lung cancer through lymphatic spread was ruled out by CT scan. 1,2 …”

Section: Differential Diagnosismentioning

confidence: 99%

Idiopathic gigantomastia in a patient on polypharmacy

et al. 2021

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Gigantomastia is an uncommon benign condition characterized by massive breast enlargement. It is most often due to hormonal imbalance secondary to puberty or pregnancy, or induced by a pharmacological agent but can also be idiopathic. Herein, we report a rare case of idiopathic gigantomastia in a 46-year-old female on antiepileptic multiple-drug therapy who underwent total bilateral mastectomy to relieve associated pain.

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Case report of bilateral inflammatory breast cancer

Cited by 5 publications

References 13 publications

Bilateral Inflammatory Breast Cancer That Developed Two Years after Treatment for Triple-negative Breast Cancer

Bilateral Inflammatory Breast Cancer That Developed Two Years after Treatment for Triple-negative Breast Cancer

Bilateral Breast Edema: Case Report and Review of the Literature

Idiopathic gigantomastia in a patient on polypharmacy

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