Case report of a primary prostatic urothelial carcinoma patient with sustained fever

Abstract

A 77-year-old-male patient presented with recurrent gross hematuria for 3 months with a fever for 1 month, and so was admitted to The First Hospital of Tsinghua University. The medical history revealed the patient exhibited no symptoms of night sweat, dysuria, or abdominal pain. The patient experienced sustained fever with maximal temperature of 39°C for 1 month without any infectious symptoms. The biochemical examination revealed that renal and hepatic function tests were normal. Serum prostate-specific antigen and free prostate-specific antigen were at a normal level. Enhanced computed tomography and magnetic resonance imaging was performed and indicated prostatic cancer with bilateral pulmonary metastases. Subsequently, prostatic urothelial carcinoma was confirmed by a histopathology assay of the prostate biopsy. Following 1 course of chemotherapy, the temperature of the patient returned to normal.

Characteristics and survival of primary urothelial carcinoma of the prostate: A multi-center retrospective study of 18 cases

“…Most of the symptoms of PUCP are non-specific lower urinary tract symptoms, including dysuria, urinary frequency, nocturia, and pain on urination [ 10 , [15] , [16] , [17] , [18] ]. Gross hematuria can also occur [ 2 , 9 , 16 , 17 ]. In our cohort, the most common symptoms of PUCP were dysuria and urinary frequency (77.8 %), followed by gross hematuria (38.9 %) and pain on urination (33.3 %).…”

“…According to 2020 global cancer statistics, prostate cancer is the second most common malignancy after lung cancer in men worldwide, over 90 % of which are prostatic adenocarcinoma [1] . Besides the urothelium of the urinary tract, urothelial carcinoma can also originate from prostatic stroma, prostatic ducts, and the mucosa of prostatic transitional urothelium, the latter being defined as primary urothelial carcinoma of the prostate (PUCP) [2] . PUCP is extremely rare, reportedly accounting for approximately 1 % to 5 % of prostatic malignancies [ 3 , 4 ].…”

Prostatic urethra recurrence after transurethral resection of bladder tumor (TURBT) for non‐muscle‐invasive bladder cancer (NMIBC)

“…9 Several case reports have described primary UC of the prostate. 10 , 11 Primary UC of the PU is rare (1%−4% of patients). 12 In contrast, the estimated incidence of bladder UC with synchronous or metachronous involvement of the prostate is reportedly between 12% and 40%.…”

“…A study has reported UC of the male anterior urethra 9 . Several case reports have described primary UC of the prostate 10,11 . Primary UC of the PU is rare (1%−4% of patients) 12 .…”

Prostatic urethra recurrence after transurethral resection of bladder tumor (TURBT) for non-muscle-invasive bladder cancer (NMIBC)

“…It does not exceed a few percent (9,10). There is also a report on male anterior urethra UC (2) There are several case reports on a primary UC of the prostate(23) (22).…”