Case report of a littoral cell angioma of the spleen and accessory spleens: A benign vascular tumour

Abstract

IntroductionLittoral- cell angioma (LCA) is a rare benign vascular tumour of the spleen. There have been less then 80 cases reported in the literature.Recent reports have described it to be a malignant lesion with congenital and immunologic associations. We report a case of LCA of the spleen.Presentation of caseA 52 -year-old male patient was admitted to hospital with a three month duration of intermittent upper abdominal pain and nausea. Imaging studies, including computer tomography (CT) and magnetic resonance imaging (MRI), showed multiple lesions in the spleen as well as in the accessory spleens.An open splenectomy was performed and his post-operative recovery was uneventful.DiscussionLittoral cell angioma of the spleen is a benign vascular tumour that has been infrequently reported in the English literature. While it does have malignant potential, the vast majority are benign. Diagnosis depends on the expression of endothelial markers like CD31 and histiocytic markers like CD68.Malignant potential is enhanced by the presence of splenomegaly as well.ConclusionThis rare condition is made even more rare by the presence of the tumour in the two accessory spleens as well.

Clinical Landscape of Littoral Cell Angioma in the Spleen Based on a Comprehensive Analysis

“…In fact, one patient developed tumor recurrence in the accessory spleen 7 years after undergoing splenectomy, which showed no significant change during the 6-month follow-up ( 16 ). According to our statistics, four patients developed LCA both in the spleen and accessory spleen ( 16 , 43 , 89 , 90 ). Therefore, it was quite reasonable to find a recurrence of LCA on the unresected accessory spleen.…”

Littoral cell splenic angioma, a rare diagnosis of abdominal pain in a child: case report and literature review

“…[4] In addition, it is important that the patient be monitored during the postoperative period to evaluate recurrence or metastasis. [10,11] A study by Bisceglia et al (1998) [12] showed that five of the twenty-one cases studied were associated with other malignancies, thus demonstrating the need for post-surgical follow-up. Postoperative complications can be prevented with prophylactic measures such as patient education, chemoprophylaxis, and immunoprophylaxis.…”