Case report of a 65-year-old man with biatrial metastatic localisation from poorly differentiated cutaneous squamous cell carcinoma

Abstract

We report the case of an immunocompetent 65-year-old man affected by cutaneous squamous cell carcinoma (cSCC) with lung and biatrial metastatic localisation. In May 2018, the patient underwent lower limb amputation due to the finding of a large ulceration which upon biopsy was found to be a poorly differentiated squamous cell carcinoma (SCC), ulcerated, full-thickness infiltrating from the skin to the underlying bone tissue. After 1 month, a radiological restaging found multiple pulmonary localisations and a right-atrial metastatic localisation. The patient was then studied in-depth and a transesophageal echocardiogram found that the patient had two 2 and 5 cm metastatic localisations in the left atrium and a 3-cm metastatic localisation in the right atrium. Informed about the clinical situation and about the risks of a chemotherapeutic treatment, the patient decided not to start any treatment. This case represents, to our knowledge, the only case of a biatrial metastatic localisation from cSCC and is representative of how cardiac symptoms and signs in patients affected by this disease must be evaluated.

Right and left atrial metastasis of renal cell carcinoma: A case report

“…To our knowledge, this is only the second reported case of bilateral atrial metastasis from RCC, and the first case to undergo surgical resection reported in the literature [8] , [9] , [11] . Biatrial metastasis has been described for other metastatic tumors such as uterine melanoma and cutaneous squamous cell carcinoma; however, these cases did not undergo resection due to poor performance statuses, making this case report the first to describe the surgical resection of biatrial metastatic cardiac tumors across all primary malignancies [12] , [13] .…”