Case report: Left ventricular noncompaction cardiomyopathy and RASopathies

Sudden cardiac arrest in the field in an 18-year-old male athlete with Noonan syndrome: case presentation and 5-year follow-up

“…It is associated with well-described cardiac anomalies including pulmonary valve stenosis (57%), secundum atrial septal defects (32%), and hypertrophic cardiomyopathy (16%), 4 as well as multiple other cardiac abnormalities. 4,5 Most deaths related to cardiac events in Noonan syndrome are related to heart failure due to progression of known structural disease. 4,6,7 Patients with minimal cardiac abnormalities typically have a good prognosis.…”