“…X-ray fluoroscopy Guide the position of the LBBP leads by contrast injection; guide HBP/LBBP leads implantation 27 Septal angiography via sheath is commonly used to estimate the depth of lead in the septum during implantation procedure 27,28,[46][47] ; with the help of angiography, distal HBP could be purposely placed on the ventricular side of the TVA 12,13 Relative subjectivity in quantifying the depth of leads and guiding the implantation of CSP lead 12,13,45 Chest Precise visualization of the venous anatomy and determination of coronary sinus and its tributaries 73 The location of CSP lead and complication assessment including lead perforation and interventricular septal hematoma 45,[74][75][76] Ionizing radiation, relatively high-dose; susceptible to beam hardening artefact from existing pacing hardware CMR Superior to CT in demonstrating mechanical dyssynchrony; better than CT at identifying septal scar, fibrosis and reversible ischemia by quantitative stress perfusion CMR provides very accurate and highresolution circumferential, radial, and longitudinal strain data using five tissue-tracking methods including myocardial tissue tagging (MR-MT) 77 with harmonic phase analysis (HARP), 78 strain-encoded imaging (SENC), 79 cine displacement encoding with stimulated echoes (DENSE), 80 velocity-encoded phase contrast MRI, 81 and manual planimetry for radial motion, 60 as well as detailed characterization of myocardial scar and viability, specifically in the basal or mid LV septum where CSP is located 33,34 Not compatible in some pacemakers and ICDs; susceptible to artefact, especially from existing MR-conditional devices (Continues)…”