Case report: Infective endocarditis caused by Streptococcus sinensis: The first case in mainland China and literature review

Abstract

Streptococcus sinensis was originally described as a causative agent for infective endocarditis in three Chinese patients from Hong Kong in 2002. Subsequently, several cases were reported outside Hong Kong, indicating that it is an emerging pathogen worldwide. We isolated a closely related strain in a young patient diagnosed with infective endocarditis in mainland China. In this paper, we reviewed the course of infection and provided a comprehensive comparison of its clinical characteristics with the reported cases.

Infective Endocarditis Caused by Streptococcus Sinensis in a Patient with Bioprosthetic Aortic Valve: A Case Report and Literature Review

“… 2 This species belongs to viridans streptococci, speculated to be the ancestor of anginosus and mitis groups of streptococci. 6 Despite the name, the species has been reported in Hong Kong, mainland China, Thailand, Switzerland, France, the Netherlands, and Britain, 2 , 3 , 7–13 demonstrating its global prevalence. Cases have been reported in both Asians and Caucasians, with some having a travel history to Asia.…”

“… 2 Until now, few cases of Streptococcus sinensis IE have been reported in Asia and Europe, with the majority of patients having congenital heart diseases or chronic rheumatic heart diseases. 3 , 4 To our knowledge, all the reported cases were native valve endocarditis. Here, we reported the first case of prosthetic valve endocarditis caused by Streptococcus sinensis worldwide.…”