Case report: Important considerations for a renal mass on a solitary kidney in an adult with history of childhood wilms tumor

Abstract

Adult survivors of childhood Wilms tumor are at an increased risk of secondary malignant neoplasms. The presence of a solitary kidney further complicates clinical management in this population. Herein, we present the case of a 37 year old female with a history of childhood Wilms tumor presenting with a secondary renal neoplasm. We highlight important clinical considerations for renal function preservation and present a finding of predisposition to kidney stone formation due to urinary stasis from distorted ureter architecture secondary to tumor mass effect.

Renal cell carcinoma in the contralateral kidney with TFE3 gene translocation following chemotherapy for childhood nephroblastoma: A case report and literature review

“…We performed a partial nephrectomy for the preservation of renal function. It has been postulated that factors associated with the preservation of postoperative renal function include younger age, higher preoperative estimated glomerular filtration rate, and greater preservation of renal parenchyma 19 . Our patient fulfilled the above factors, which may have led to successful protection of postoperative renal function.…”

“…It has been postulated that factors associated with the preservation of postoperative renal function include younger age, higher preoperative estimated glomerular filtration rate, and greater preservation of renal parenchyma. 19 Our patient fulfilled the above factors, which may have led to successful protection of postoperative renal function. In our review (Table 1 2,[7][8][9][10][11][12][13][14][15] ), six cases underwent partial nephrectomy as surgical treatment.…”