Case Report: Bullous Scabies in Two Children below 10 Years

Luo, Zeyu; Zeng, Mei Chun; Gao, Qian; Zhao, Yanyang; Sarkar, Rashmi; Liao, Shuping; Luo, Di‐Qing

doi:10.4269/ajtmh.17-0344

Cited by 11 publications

(18 citation statements)

References 8 publications

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“…These criteria may also provide a basis for the development of teaching and training tools for scabies diagnosis. 28 The 2020 IACS Criteria are not intended for use in the diagnosis of variant or atypical presentations of scabies, such as crusted scabies; bullous scabies; 29,30 scabies in immunocompromised individuals; or scabies in elderly, cognitively impaired or bedridden individuals. 7,[31][32][33] Previously administered treatments, including topical or systemic corticosteroids, often modify the symptoms and signs and confound diagnosis.…”

Section: Development and Intent Of Standardized Criteriamentioning

confidence: 99%

The 2020 International Alliance for the Control of Scabies Consensus Criteria for the Diagnosis of Scabies

et al. 2020

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Summary Background Scabies is a common parasitic skin condition that causes considerable morbidity globally. Clinical and epidemiological research for scabies has been limited by a lack of standardization of diagnostic methods. Objectives To develop consensus criteria for the diagnosis of common scabies that could be implemented in a variety of settings. Methods Consensus diagnostic criteria were developed through a Delphi study with international experts. Detailed recommendations were collected from the expert panel to define the criteria features and guide their implementation. These comments were then combined with a comprehensive review of the available literature and the opinion of an expanded group of international experts to develop detailed, evidence‐based definitions and diagnostic methods. Results The 2020 International Alliance for the Control of Scabies (IACS) Consensus Criteria for the Diagnosis of Scabies include three levels of diagnostic certainty and eight subcategories. Confirmed scabies (level A) requires direct visualization of the mite or its products. Clinical scabies (level B) and suspected scabies (level C) rely on clinical assessment of signs and symptoms. Evidence‐based, consensus methods for microscopy, visualization and clinical symptoms and signs were developed, along with a media library. Conclusions The 2020 IACS Criteria represent a pragmatic yet robust set of diagnostic features and methods. The criteria may be implemented in a range of research, public health and clinical settings by selecting the appropriate diagnostic levels and subcategories. These criteria may provide greater consistency and standardization for scabies diagnosis. Validation studies, development of training materials and development of survey methods are now required. What is already known about this topic? The diagnosis of scabies is limited by the lack of accurate, objective tests. Microscopy of skin scrapings can confirm the diagnosis, but it is insensitive, invasive and often impractical. Diagnosis usually relies on clinical assessment, although visualization using dermoscopy is becoming increasingly common. These diagnostic methods have not been standardized, hampering the interpretation of findings from clinical research and epidemiological surveys, and the development of scabies control strategies. What does this study add? International consensus diagnostic criteria for common scabies were developed through a Delphi study with global experts. The 2020 International Alliance for the Control of Scabies (IACS) Criteria categorize diagnosis at three levels of diagnostic certainty (confirmed, clinical and suspected scabies) and eight subcategories, and can be adapted to a range of research and public health settings. Detailed definitions and figures are included to aid training and implementation. The 2020 IACS Criteria may facilitate the standardization of scabies diagnosis.

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Section: Development and Intent Of Standardized Criteriamentioning

confidence: 99%

The 2020 International Alliance for the Control of Scabies Consensus Criteria for the Diagnosis of Scabies

et al. 2020

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“…The other subtype of scabies, which seems to be the most severe, is bullous scabies (also called bullous pemphigoid-like eruptions) with atypical symptoms mimicking bullous pemphigoid [ 24 , 25 ] but with a negative Nikolsky’s sign [ 26 ]. In bullous scabies, the mites or their secretions may cause alterations or the release of bullous pemphigoid antigen, leading to an immunological response and resulting in the production of antibasement membrane zone antibodies, as seen in bullous pemphigoid [ 27 ].…”

Section: Biology and Pathophysiology Of Sarcoptes Infestationmentioning

confidence: 99%

Sarcoptes Infestation. What Is Already Known, and What Is New about Scabies at the Beginning of the Third Decade of the 21st Century?

Talaga-Ćwiertnia

2021

Pathogens

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Currently, there are three known subtypes of scabies: ordinary, crusted, and bullous. The worldwide prevalence of scabies remains high in the 21st century. To decrease the social, economic, and psychological impact on the enormous population infected, a lot of important work has been completed over the last 20 years concerning the management of scabies. For example, a standardization of guidelines for the treatment of scabies has been completed and programs have been designed for the prevention and treatment in endemic populations, called mass drug administrations. Unfortunately, these only apply to the ordinary form of scabies. Moreover, resistance to the drugs currently used in treatment is growing, which imposes the need to search for new treatments. For this purpose, new acaricides are being developed to enhance the therapeutic options for the patients’ benefit and effectively treat this disease. There is also the necessity for prevention before the development of scabies. An effective vaccine has the potential to protect people before this disease, especially in endemic areas. Unfortunately, there are no such vaccines against Sarcoptes yet.

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“…A bullosus scabies ritkán észlelhető hólyagos tünetei autoimmun hólyagos bőrbetegségeket utánozhatnak [13].…”

Section: A Rühatkafélék Családjaunclassified

Atkafélék okozta, bőrtünetekkel járó humán megbetegedések

Budai

Barna

Nagy

2021

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Összefoglaló. Az atkák alosztálya heterogén csoport. Az eltérő megjelenésű és életformájú atkák növényeken, állatokon és embereken is képesek különféle megbetegedéseket okozni, melyek csípés, táplálkozás, élősködés, vektorként terjesztett kórokozók által valósulhatnak meg. Az atkák okozta betegségek a lokális, spontán szűnő csípéstől egészen a sokszervi elégtelenséget okozó fertőző betegségig széles skálán mozognak. Munkánk során az atkafélék által okozott humán megbetegedések előfordulását, klinikai megjelenését, differenciáldiagnosztikáját, kezelését és közegészségügyi jelentőségét mutatjuk be. Orv Hetil. 2021; 162(36): 1430–1437. Summary. The Acari subclass is a heterogeneous group. They have different appearance and lifestyle. They can cause different diseases on plants, in animals and in humans. These illnesses can be caused by their bites, nutrition, parasitism and by their endoparasites. The diseases move on a wide scale from a local, spontaneously disappearing bite to an infection caused multiorgan failure. We would like to summarize the Acari-caused human diseases’ incidence, clinical symptoms, diagnostics, differential diagnostics, treatments and public health importance. Orv Hetil. 2021; 162(36): 1430–1437.

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Case Report: Bullous Scabies in Two Children below 10 Years

Cited by 11 publications

References 8 publications

The 2020 International Alliance for the Control of Scabies Consensus Criteria for the Diagnosis of Scabies

The 2020 International Alliance for the Control of Scabies Consensus Criteria for the Diagnosis of Scabies

Sarcoptes Infestation. What Is Already Known, and What Is New about Scabies at the Beginning of the Third Decade of the 21st Century?

Atkafélék okozta, bőrtünetekkel járó humán megbetegedések

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