Case report: An exceptional mode of revelation of hodgkin’s disease: acute CMV hepatitis

Abstract

Hodgkin's disease is reported especially in young age, suspected in the presence of suspicious lymphadenopathy. Its revelation by acute hepatitis remains very exceptional. We report the case of a 25-year-old admitted in the emergency department for a febrile cholestatic jaundice, an erythroderma, an epistaxis with gingivorragias and edema of the lower limbs. Clinical examination revealed bilateral retroauricular and inguinal lymphadenopathy. The diagnosis of acute CMV hepatitis was based on the positivity of serology and Polymerase chain reaction "PCR". Anatomopathological and immunohistochemical examination of lymphadenopathy confirmed the diagnosis of Hodgkin's disease. CMV hepatitis is not exceptional in an immunocompromised patient, what is exceptional in our observation is the fact that it has ushered an Hodgkin's disease.