“…Most authors believe that cutaneous WD is derived from the hair follicle because of its closeness or clear-cut connection to pilosebaceous unit, 3,[5][6][7]9 thereby suggesting that "follicular dyskeratoma" might be a better term for this entity. 6 A study performed with human keratin antibodies, specific for cortex and inner root sheet of normal human hair, 8 and a survey carried out searching the expression of cytokeratins CK 1 , CK 5 , Ck 10 , CK 17 , CK 19 5 confirmed this hypothesis. WD arising in regions devoid of follicular structures (oral mucosa 12 and nail bed 13,14 ) may represent examples of isolated FAD secondary to a local inflammation or a neoplastic proliferation.…”