Abstract:Background: Serotonergic antidepressants inhibit platelet aggregation, and use of these drugs has been associated with adverse bleeding events. The objective of this study was to determine the association of preoperative use of serotonergic antidepressants and perioperative bleeding in patients undergoing total knee arthroplasty. Methods: A retrospective analysis was conducted of 80 patients who underwent elective primary total knee arthroplasty in a large hospital. The index group included 40 patients who use… Show more
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