Case of Solitary Peritoneal Metastasis From Atypical Bronchopulmonary Carcinoid on 18F-FDG PET/CT

Abstract

Atypical lung carcinoids frequently metastasize to mediastinal nodes, liver, bone, lungs, and brain and rarely to ovaries, pancreas, subcutaneous, and skin. Solitary peritoneal metastasis is extremely rare and unreported previously. We present a case of a 36-year-old woman with cough, hemoptysis, dyspnea with detection of lung mass, and incidental detection of pelvic mass. Fine needle aspiration cytology failed to reveal the true nature of both the lesions. FDG PET/CT showed intensely avid mediastinal nodes, left lung, and rectouterine masses. Core biopsy from lung mass revealed atypical carcinoid without appreciable uptake on 68Ga-DOTANOC scan. Subsequent postchemotherapy CT scan shows significant regression in lung and peritoneal masses.

Diagnostic and clinical value of F-18 FDG PET/CT in thoracic carcinoid tumors

“…18 F-fluorodeoxyglucose positron emission tomography (FDG-PET) is the used for diagnosis of carcinoid tumors [4]. In the differential diagnosis of carcinoid tumors, the prevalence of which has increased in recent years, from lung masses, it is aimed to reflect the additional information and metabolic data to be provided by F-18 FDG PET/CT to the clinic, to identify some determinative features in the diagnosis of carcinoid tumors, and to include them in clinical practice to contribute positively to the prognosis of the patients [4,5]. In their study published in the 2023 edition of the Annals of Nuclear Medicine by Flavia Linguanti et al, the prognostic significance of volumetric and semiquantitative parameters measured using [18F]FDG PET/CT imaging in patients with typical lung carcinoids and their relationship with the proliferative index (Ki-67) were evaluated [6].…”