Case of pneumatosis cystoides intestinalis in adult dermatomyositis

Xiao, Ting; Xu, Hongen; Wu, Jiahui; He, Chundi; Chen, Hong‐Duo

doi:10.1111/j.1346-8138.2007.00414.x

Cited by 11 publications

(5 citation statements)

References 9 publications

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“…The emergence of gas into the bowel wall, with or without free gas in the peritoneal cavity, is defined as PCI 1–3 . Intestinal involvement in SSc, 1–9 dermatomyositis (DM) or PM, 10–17 and mixed CTD 18–25 may be complicated by PCI. The appearance of PCI in systemic lupus erythematosus (SLE), 26 relapsing polychondritis 27 and primary Sjogren's syndrome 28 has been reported.…”

Section: Discussionmentioning

confidence: 99%

Pneumatosis cystoides intestinalis in scleroderma‐related conditions

Balbir‐Gurman

Brook

Chermesh

et al. 2012

Internal Medicine Journal

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Section: Discussionmentioning

confidence: 99%

Pneumatosis cystoides intestinalis in scleroderma‐related conditions

Balbir‐Gurman

Brook

Chermesh

et al. 2012

Internal Medicine Journal

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“…Mucosal infection or injury may easily cause penetration of intraluminal air into the intestinal wall, leading to the development of PCI. Highdose corticosteroid and its long-term use have been reported as an essentially harmful factor causing PCI in SLE [16,19,21,22,24,25], as well as other autoimmune disorders, such as inflammatory myopathy [28,29]. Voglibose, an aGI, reduces the absorption speed of carbohydrates from the intestine, and acts as an anti-diabetic drug.…”

Section: Discussionmentioning

confidence: 99%

Pneumatosis cystoides intestinalis in neuropsychiatric systemic lupus erythematosus with diabetes mellitus: case report and literature review

et al. 2011

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We report a patient with neuropsychiatric systemic lupus erythematosus (NPSLE) complicated by diabetes mellitus (DM) who showed pneumatosis cystoides intestinalis (PCI) while being treated with prednisolone (PSL) and an alpha-glucosidase inhibitor (αGI). The PCI was ameliorated with the cessation of the αGI and tapering of PSL in addition to transient fasting. Multiple factors, including NPSLE, DM, and medications, may have been involved in the pathogenesis of PCI in this patient.

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“…PCI is characterized by the development of multiple submucosal or subserosal pneumatocysts in the submucosa or subserosa of the colon [3-5]. An abdominal X-ray and CT demonstrated pneumoperitoneum with massive air accumulation in the intestinal wall, particularly in the colon, leading to the diagnosis of PCI [6].…”

Section: Discussionmentioning

confidence: 99%

Improvement of pneumatosis cystoides intestinalis after steroid tapering in a patient with bronchial asthma: a case report

et al. 2013

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IntroductionWe report the case of a patient who was diagnosed as having pneumatosis cystoides intestinalis while being treated with prednisolone for bronchial asthma. Even before we had experienced a case of this, the relationship between pneumatosis cystoides intestinalis and prednisolone was unclear. In this case, pneumatosis cystoides intestinalis was improved with the reduction of prednisolone, and therefore we thought a direct relationship between pneumatosis cystoides intestinalis and prednisolone might become clear, such as whether it is dose dependent.Case presentationA 62-year-old Japanese woman had been treated for bronchial asthma for approximately 40 years. She presented with abdominal distension, and a radiographic examination showed intraperitoneal free gas and intramural gas, suggestive of pneumatosis cystoides intestinalis. However, when her prednisolone dose was decreased from 30mg to 0mg for approximately a year because of improvement in her asthma symptoms, her abdominal symptom resolved, and the frequency of her bowel movements returned to normal.ConclusionAmelioration of pneumatosis cystoides intestinalis was observed with tapering of the prednisolone, suggesting that prednisolone may have been involved in the pathogenesis of pneumatosis cystoides intestinalis in this patient.

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Case of pneumatosis cystoides intestinalis in adult dermatomyositis

Cited by 11 publications

References 9 publications

Pneumatosis cystoides intestinalis in scleroderma‐related conditions

Pneumatosis cystoides intestinalis in scleroderma‐related conditions

Pneumatosis cystoides intestinalis in neuropsychiatric systemic lupus erythematosus with diabetes mellitus: case report and literature review

Improvement of pneumatosis cystoides intestinalis after steroid tapering in a patient with bronchial asthma: a case report

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