Case of pemphigoid involving skin and mucous membrane with immunoglobulin G autoantibodies targeted to BP180 and laminin‐332

Case of subepidermal bullous disease with diffuse esophageal involvement presenting with immunoglobulin G autoantibodies to both the BP180 NC16a and C‐terminal domains, and immunoglobulin A autoantibodies to the BP180 NC16a domain

“…4 There are several reports of MMP cases in which IgG antibodies to both the BP180 C-terminal domain and laminin-332 play a pathogenic role. 5 Thus, in our case, IgG antibodies to both the BP180 NC16a and C-terminal …”

“…Among them, the presence of antibodies to BP180 or BP230 was described only in two cases. The case reported by Chan et al 4 had autoantibodies to BP230, and the case by Suda-Takayanagi et al 5 had antibodies to both BP180 and BP230 antigens.…”